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Presence and persistence of australia antigen in patients with liver disorders

Nordenfelt, Erik and Dahlquist, Erik (1970) In Scandinavian Journal of Infectious Diseases 2(3). p.167-171
Abstract

Patients with suspected disease involving the liver and seen at a department for infectious diseases were examined routinely for Au-antigen. Of 344 patients examined, 259 were found to have biochemical evidence of liver affection. Acute hepatitis was diagnosed in 129, including 65 with serum hepatitis, 18 with infections hepatitis and 46 with sporadic hepatitis. 62 patients had Au-antigen and 60 of them belonged to the group acute hepatitis. 69% of the patients with serum hepatitis and 28% of those with sporadic hepatitis were Au-antigen positive. Most of the patients harboured the antigen only temporarily. It was demonstrated up to 2-7 weeks after anamnestic onset. In 5 patients Au-antigen in the serum persisted for 5-15 months;... (More)

Patients with suspected disease involving the liver and seen at a department for infectious diseases were examined routinely for Au-antigen. Of 344 patients examined, 259 were found to have biochemical evidence of liver affection. Acute hepatitis was diagnosed in 129, including 65 with serum hepatitis, 18 with infections hepatitis and 46 with sporadic hepatitis. 62 patients had Au-antigen and 60 of them belonged to the group acute hepatitis. 69% of the patients with serum hepatitis and 28% of those with sporadic hepatitis were Au-antigen positive. Most of the patients harboured the antigen only temporarily. It was demonstrated up to 2-7 weeks after anamnestic onset. In 5 patients Au-antigen in the serum persisted for 5-15 months; histologic examination of biopsy specimen showed signs of chronic liver disease in 4, only mild changes in 1. Only 3 patients had antibodies in the serum; all of them had been exposed to antigen for a long time. In one patient with arthritis Au-antigen was repeatedly demonstrated in both serum and joint exudate. © 1970, Informa UK Ltd. All rights reserved.

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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Australian antigen, liver disorders
in
Scandinavian Journal of Infectious Diseases
volume
2
issue
3
pages
5 pages
publisher
Informa Healthcare
external identifiers
  • Scopus:84961447635
ISSN
0036-5548
DOI
10.3109/inf.1970.2.issue-3.03
language
English
LU publication?
no
id
8550e474-e8b3-4f2f-820a-790b5297da6e
date added to LUP
2016-05-19 14:46:07
date last changed
2016-11-27 04:40:33
@misc{8550e474-e8b3-4f2f-820a-790b5297da6e,
  abstract     = {<p>Patients with suspected disease involving the liver and seen at a department for infectious diseases were examined routinely for Au-antigen. Of 344 patients examined, 259 were found to have biochemical evidence of liver affection. Acute hepatitis was diagnosed in 129, including 65 with serum hepatitis, 18 with infections hepatitis and 46 with sporadic hepatitis. 62 patients had Au-antigen and 60 of them belonged to the group acute hepatitis. 69% of the patients with serum hepatitis and 28% of those with sporadic hepatitis were Au-antigen positive. Most of the patients harboured the antigen only temporarily. It was demonstrated up to 2-7 weeks after anamnestic onset. In 5 patients Au-antigen in the serum persisted for 5-15 months; histologic examination of biopsy specimen showed signs of chronic liver disease in 4, only mild changes in 1. Only 3 patients had antibodies in the serum; all of them had been exposed to antigen for a long time. In one patient with arthritis Au-antigen was repeatedly demonstrated in both serum and joint exudate. © 1970, Informa UK Ltd. All rights reserved.</p>},
  author       = {Nordenfelt, Erik and Dahlquist, Erik},
  issn         = {0036-5548},
  keyword      = {Australian antigen,liver disorders},
  language     = {eng},
  number       = {3},
  pages        = {167--171},
  publisher    = {ARRAY(0x9f17fb8)},
  series       = {Scandinavian Journal of Infectious Diseases},
  title        = {Presence and persistence of australia antigen in patients with liver disorders},
  url          = {http://dx.doi.org/10.3109/inf.1970.2.issue-3.03},
  volume       = {2},
  year         = {1970},
}