Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint.
(2016) In Journal of the American Heart Association 5(3). p.002708-002708- Abstract
- Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of biochemical markers in clinical cardioprotection trials and how scan day affect sample size.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8852796
- author
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the American Heart Association
- volume
- 5
- issue
- 3
- pages
- 002708 - 002708
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:26961520
- wos:000385312200017
- pmid:26961520
- scopus:85006186650
- ISSN
- 2047-9980
- DOI
- 10.1161/JAHA.115.002708
- language
- English
- LU publication?
- yes
- id
- 04a658fc-df51-43c1-a14b-0c4919275f69 (old id 8852796)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26961520?dopt=Abstract
- date added to LUP
- 2016-04-04 09:05:39
- date last changed
- 2022-02-20 23:11:40
@article{04a658fc-df51-43c1-a14b-0c4919275f69, abstract = {{Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of biochemical markers in clinical cardioprotection trials and how scan day affect sample size.}}, author = {{Engblom, Henrik and Heiberg, Einar and Erlinge, David and Jensen, Svend Eggert and Nordrehaug, Jan Erik and Dubois-Randé, Jean-Luc and Halvorsen, Sigrun and Hoffmann, Pavel and Koul, Sasha and Carlsson, Marcus and Atar, Dan and Arheden, Håkan}}, issn = {{2047-9980}}, language = {{eng}}, number = {{3}}, pages = {{002708--002708}}, publisher = {{Wiley-Blackwell}}, series = {{Journal of the American Heart Association}}, title = {{Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint.}}, url = {{http://dx.doi.org/10.1161/JAHA.115.002708}}, doi = {{10.1161/JAHA.115.002708}}, volume = {{5}}, year = {{2016}}, }