Advanced

Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint.

Engblom, Henrik LU ; Heiberg, Einar LU ; Erlinge, David LU ; Jensen, Svend Eggert; Nordrehaug, Jan Erik; Dubois-Randé, Jean-Luc; Halvorsen, Sigrun; Hoffmann, Pavel; Koul, Sasha LU and Carlsson, Marcus LU , et al. (2016) In Journal of the American Heart Association 5(3). p.002708-002708
Abstract
Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of biochemical markers in clinical cardioprotection trials and how scan day affect sample size.
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of the American Heart Association
volume
5
issue
3
pages
002708 - 002708
publisher
Wiley-Blackwell
external identifiers
  • PMID:26961520
ISSN
2047-9980
DOI
10.1161/JAHA.115.002708
language
English
LU publication?
yes
id
04a658fc-df51-43c1-a14b-0c4919275f69 (old id 8852796)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26961520?dopt=Abstract
date added to LUP
2016-03-15 14:19:00
date last changed
2016-04-16 06:12:11
@misc{04a658fc-df51-43c1-a14b-0c4919275f69,
  abstract     = {Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of biochemical markers in clinical cardioprotection trials and how scan day affect sample size.},
  author       = {Engblom, Henrik and Heiberg, Einar and Erlinge, David and Jensen, Svend Eggert and Nordrehaug, Jan Erik and Dubois-Randé, Jean-Luc and Halvorsen, Sigrun and Hoffmann, Pavel and Koul, Sasha and Carlsson, Marcus and Atar, Dan and Arheden, Håkan},
  issn         = {2047-9980},
  language     = {eng},
  number       = {3},
  pages        = {002708--002708},
  publisher    = {ARRAY(0xb1dd358)},
  series       = {Journal of the American Heart Association},
  title        = {Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint.},
  url          = {http://dx.doi.org/10.1161/JAHA.115.002708},
  volume       = {5},
  year         = {2016},
}