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Breath-holding spells occur disproportionately more often in children with transient erythroblastopenia

Schmidt, Sanna Hellström; Tedgård, Ulf LU and Pronk, Kees-Jan LU (2016) In Acta Pædiatrica 105(9). p.1088-1093
Abstract

AIM: This study aimed to evaluate the concomitant occurrence and possible association of breath-holding spells (BHS) and transient erythroblastopenia of childhood (TEC).

METHODS: This population-based cohort study, carried out in Southern Sweden from 2004-2014, included patients with BHS and, or, anaemia, including TEC. The subjects were evaluated for the presence of all three conditions and the diagnostic workups, disease characteristics and outcome were analysed.

RESULTS: We studied 443,470 children under the age of 10 years old during 2004-2014. The total cohort included 321 patients (0.07%) with BHS and 366 patients with a selection of anaemia diagnoses, including 41 with TEC. We found that nine (2.5%) of the 366... (More)

AIM: This study aimed to evaluate the concomitant occurrence and possible association of breath-holding spells (BHS) and transient erythroblastopenia of childhood (TEC).

METHODS: This population-based cohort study, carried out in Southern Sweden from 2004-2014, included patients with BHS and, or, anaemia, including TEC. The subjects were evaluated for the presence of all three conditions and the diagnostic workups, disease characteristics and outcome were analysed.

RESULTS: We studied 443,470 children under the age of 10 years old during 2004-2014. The total cohort included 321 patients (0.07%) with BHS and 366 patients with a selection of anaemia diagnoses, including 41 with TEC. We found that nine (2.5%) of the 366 patients with anaemia diagnoses also had BHS and that five (12.2%) of the 41 patients with TEC patients also had BHS. Treatment for anaemia resolved BHS in a number of patients.

CONCLUSION: Our population-based analysis revealed an overrepresentation of BHS among children with TEC and we identified five patients with concomitant TEC and BHS. We found that correcting anaemia was an effective means of ameliorating potentially debilitating BHS and that the presence of concomitant BHS and TEC was more common than previously assumed. This article is protected by copyright. All rights reserved.

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author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
in
Acta Pædiatrica
volume
105
issue
9
pages
1088 - 1093
publisher
Taylor & Francis
external identifiers
  • Scopus:84987940255
ISSN
1651-2227
DOI
10.1111/apa.13428
language
English
LU publication?
yes
id
8c6f0e2e-a8af-4b31-abcd-e004f8d2a1b2
date added to LUP
2016-05-03 14:22:32
date last changed
2016-11-06 04:37:23
@misc{8c6f0e2e-a8af-4b31-abcd-e004f8d2a1b2,
  abstract     = {<p>AIM: This study aimed to evaluate the concomitant occurrence and possible association of breath-holding spells (BHS) and transient erythroblastopenia of childhood (TEC).</p><p>METHODS: This population-based cohort study, carried out in Southern Sweden from 2004-2014, included patients with BHS and, or, anaemia, including TEC. The subjects were evaluated for the presence of all three conditions and the diagnostic workups, disease characteristics and outcome were analysed.</p><p>RESULTS: We studied 443,470 children under the age of 10 years old during 2004-2014. The total cohort included 321 patients (0.07%) with BHS and 366 patients with a selection of anaemia diagnoses, including 41 with TEC. We found that nine (2.5%) of the 366 patients with anaemia diagnoses also had BHS and that five (12.2%) of the 41 patients with TEC patients also had BHS. Treatment for anaemia resolved BHS in a number of patients.</p><p>CONCLUSION: Our population-based analysis revealed an overrepresentation of BHS among children with TEC and we identified five patients with concomitant TEC and BHS. We found that correcting anaemia was an effective means of ameliorating potentially debilitating BHS and that the presence of concomitant BHS and TEC was more common than previously assumed. This article is protected by copyright. All rights reserved.</p>},
  author       = {Schmidt, Sanna Hellström and Tedgård, Ulf and Pronk, Kees-Jan},
  issn         = {1651-2227},
  language     = {eng},
  month        = {04},
  number       = {9},
  pages        = {1088--1093},
  publisher    = {ARRAY(0x9e88f08)},
  series       = {Acta Pædiatrica},
  title        = {Breath-holding spells occur disproportionately more often in children with transient erythroblastopenia},
  url          = {http://dx.doi.org/10.1111/apa.13428},
  volume       = {105},
  year         = {2016},
}