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What is the current status of biochemical markers in the diagnosis, prognosis and monitoring of osteoarthritis?

Lohmander, L. S. LU (1997) In Baillière's Clinical Rheumatology 11(4). p.711-726
Abstract

Biochemical markers for osteoarthritis (OA) may serve different purposes. Since markers reflect ongoing dynamic metabolic processes in the joint tissues (cartilage, synovium, bone, etc.), they are most likely to be useful to predict prognosis and response to treatment, to monitor response to treatment, and for disease staging. Markers are currently being used at the research level for these purposes. The goal of using these markers to assess the disease process in the OA clinical trial setting or in the clinical routine has, however, not yet been reached.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cartilage, Collagen, Metabolism, Osteoarthritis, Proteoglycan, Synovial fluid
in
Baillière's Clinical Rheumatology
volume
11
issue
4
pages
16 pages
publisher
Elsevier
external identifiers
  • Scopus:0031453694
ISSN
0950-3579
DOI
10.1016/S0950-3579(97)80006-4
language
English
LU publication?
yes
id
96e482d1-69b7-4299-94c8-56d8db6f8e1f
date added to LUP
2016-05-04 23:53:32
date last changed
2016-08-04 15:09:29
@misc{96e482d1-69b7-4299-94c8-56d8db6f8e1f,
  abstract     = {<p>Biochemical markers for osteoarthritis (OA) may serve different purposes. Since markers reflect ongoing dynamic metabolic processes in the joint tissues (cartilage, synovium, bone, etc.), they are most likely to be useful to predict prognosis and response to treatment, to monitor response to treatment, and for disease staging. Markers are currently being used at the research level for these purposes. The goal of using these markers to assess the disease process in the OA clinical trial setting or in the clinical routine has, however, not yet been reached.</p>},
  author       = {Lohmander, L. S.},
  issn         = {0950-3579},
  keyword      = {Cartilage,Collagen,Metabolism,Osteoarthritis,Proteoglycan,Synovial fluid},
  language     = {eng},
  number       = {4},
  pages        = {711--726},
  publisher    = {ARRAY(0xa3bb250)},
  series       = {Baillière's Clinical Rheumatology},
  title        = {What is the current status of biochemical markers in the diagnosis, prognosis and monitoring of osteoarthritis?},
  url          = {http://dx.doi.org/10.1016/S0950-3579(97)80006-4},
  volume       = {11},
  year         = {1997},
}