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Gradient echo imaging of flowing hyperpolarized nuclei : theory and phantom studies on 129Xe dissolved in ethanol

Johansson, Edvin LU ; Svensson, Jonas LU ; Månsson, S LU ; Petersson, J S LU ; Olsson, L E LU ; Golman, K LU and Ståhlberg, F LU (2002) In Journal of Magnetic Resonance 159(1). p.68-75
Abstract

The influence of flip angle and flow velocity on the signal intensity achieved when imaging a hyperpolarized substance with a spoiled gradient echo sequence was investigated. The study was performed both theoretically and experimentally using hyperpolarized xenon dissolved in ethanol. Analytical expressions regarding the optimal flip angle with respect to signal and the corresponding signal level are presented and comparisons with thermally polarized substances are made. Both experimentally and theoretically, the optimal flip angle was found to increase with increasing flow velocity. Numerical calculations showed that the velocity dependence of the signal differs between the cases of hyperpolarized and thermally polarized substances.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Echo-Planar Imaging, Ethanol, Magnetic Resonance Angiography, Phantoms, Imaging, Xenon Isotopes
in
Journal of Magnetic Resonance
volume
159
issue
1
pages
8 pages
publisher
Elsevier
external identifiers
  • Scopus:0036920254
ISSN
1090-7807
DOI
10.1016/S1090-7807(02)00117-9
language
English
LU publication?
yes
id
9cba2f25-3ab1-4ecf-a556-400733afe7e0
date added to LUP
2016-08-16 12:12:24
date last changed
2016-10-13 05:12:17
@misc{9cba2f25-3ab1-4ecf-a556-400733afe7e0,
  abstract     = {<p>The influence of flip angle and flow velocity on the signal intensity achieved when imaging a hyperpolarized substance with a spoiled gradient echo sequence was investigated. The study was performed both theoretically and experimentally using hyperpolarized xenon dissolved in ethanol. Analytical expressions regarding the optimal flip angle with respect to signal and the corresponding signal level are presented and comparisons with thermally polarized substances are made. Both experimentally and theoretically, the optimal flip angle was found to increase with increasing flow velocity. Numerical calculations showed that the velocity dependence of the signal differs between the cases of hyperpolarized and thermally polarized substances.</p>},
  author       = {Johansson, Edvin and Svensson, Jonas and Månsson, S and Petersson, J S and Olsson, L E and Golman, K and Ståhlberg, F},
  issn         = {1090-7807},
  keyword      = {Echo-Planar Imaging,Ethanol,Magnetic Resonance Angiography,Phantoms, Imaging,Xenon Isotopes},
  language     = {eng},
  number       = {1},
  pages        = {68--75},
  publisher    = {ARRAY(0xb8d3bc8)},
  series       = {Journal of Magnetic Resonance},
  title        = {Gradient echo imaging of flowing hyperpolarized nuclei : theory and phantom studies on 129Xe dissolved in ethanol},
  url          = {http://dx.doi.org/10.1016/S1090-7807(02)00117-9},
  volume       = {159},
  year         = {2002},
}