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Differential molecular and behavioural response to L-DOPA in mice injected with 6-hydroxydopamine in the striatum or in the medial forebrain bundle

Francardo, Veronica LU ; Recchia, Alessandra LU ; Mohammed, Mohsin LU ; Nissbrandt, Hans and Cenci Nilsson, Angela LU (2010)
Abstract
Unilateral lesions of nigrostriatal dopamine ( DA) pathways with 6-hydroxydopamine (6-OHDA) can be used to obtain a model of Parkinson's disease in the mouse. In the present study we examine two types of unilateral 6-OHDA lesions in the mouse for their ability to induce stable motor deficits and supersensitive molecular and behavioural response to L-DOPA.
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author
organization
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Contribution to conference
publication status
published
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keywords
L-DOPA, 6-OHDA, mice
language
English
LU publication?
yes
id
a892222d-82eb-41d3-bd89-4dd1ceb5540f
date added to LUP
2016-06-02 10:38:19
date last changed
2016-06-08 15:52:27
@misc{a892222d-82eb-41d3-bd89-4dd1ceb5540f,
  abstract     = {Unilateral lesions of nigrostriatal dopamine  ( DA) pathways with 6-hydroxydopamine (6-OHDA)  can be used to obtain a model of Parkinson's disease in the mouse. In the present study we examine two types of unilateral 6-OHDA lesions in the mouse for their ability to induce stable motor deficits and supersensitive molecular and behavioural response to L-DOPA.},
  author       = {Francardo, Veronica and Recchia, Alessandra and Mohammed, Mohsin and Nissbrandt, Hans and Cenci Nilsson, Angela},
  keyword      = {L-DOPA,6-OHDA,mice},
  language     = {eng},
  title        = {Differential molecular and behavioural response to L-DOPA in mice injected with 6-hydroxydopamine in the striatum or in the medial forebrain bundle},
  year         = {2010},
}