Difference in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis.
(1985) In The Lancet 2/8447(8447). p.127-128- Abstract
- Cartilage proteoglycans were measured, by the use of an enzyme-linked immunosorbent assay, in synovial fluids obtained from 109 unselected patients attending an outpatient rheumatology clinic because of inflammation of the knee. The content of proteoglycans in synovial fluid was inversely related to the degree of joint destruction shown on X-ray. The proteoglycan concentrations in knee-joint exudates were higher in patients with reactive arthritis than in patients with rheumatoid arthritis having synovitis of corresponding duration and lacking radiological evidence of cartilage destruction. The measurement of proteoglycan levels may therefore be useful in differentiating between the two conditions.
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- author
- Saxne, Tore LU ; Heinegård, Dick LU ; Wollheim, Frank LU and Petersson, H
- organization
- publishing date
- 1985
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- CARTILAGE PROTEOGLYCAN, RHEUMATOID ARTHRITIS, SYNOVIAL FLUID
- in
- The Lancet
- volume
- 2/8447
- issue
- 8447
- pages
- 127 - 128
- publisher
- Elsevier
- external identifiers
-
- scopus:0021889712
- ISSN
- 1474-547X
- language
- English
- LU publication?
- yes
- id
- bc54368d-d6b3-41af-af8f-1d14aac3fa73
- date added to LUP
- 2016-05-06 15:45:39
- date last changed
- 2021-09-26 04:56:12
@article{bc54368d-d6b3-41af-af8f-1d14aac3fa73, abstract = {{Cartilage proteoglycans were measured, by the use of an enzyme-linked immunosorbent assay, in synovial fluids obtained from 109 unselected patients attending an outpatient rheumatology clinic because of inflammation of the knee. The content of proteoglycans in synovial fluid was inversely related to the degree of joint destruction shown on X-ray. The proteoglycan concentrations in knee-joint exudates were higher in patients with reactive arthritis than in patients with rheumatoid arthritis having synovitis of corresponding duration and lacking radiological evidence of cartilage destruction. The measurement of proteoglycan levels may therefore be useful in differentiating between the two conditions.}}, author = {{Saxne, Tore and Heinegård, Dick and Wollheim, Frank and Petersson, H}}, issn = {{1474-547X}}, keywords = {{CARTILAGE PROTEOGLYCAN; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID}}, language = {{eng}}, number = {{8447}}, pages = {{127--128}}, publisher = {{Elsevier}}, series = {{The Lancet}}, title = {{Difference in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis.}}, volume = {{2/8447}}, year = {{1985}}, }