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Difference in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis.

Saxne, Tore LU ; Heinegård, Dick LU ; Wollheim, Frank LU and Petersson, H (1985) In Lancet 2/8447(8447). p.127-128
Abstract
Cartilage proteoglycans were measured, by the use of an enzyme-linked immunosorbent assay, in synovial fluids obtained from 109 unselected patients attending an outpatient rheumatology clinic because of inflammation of the knee. The content of proteoglycans in synovial fluid was inversely related to the degree of joint destruction shown on X-ray. The proteoglycan concentrations in knee-joint exudates were higher in patients with reactive arthritis than in patients with rheumatoid arthritis having synovitis of corresponding duration and lacking radiological evidence of cartilage destruction. The measurement of proteoglycan levels may therefore be useful in differentiating between the two conditions.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
CARTILAGE PROTEOGLYCAN , RHEUMATOID ARTHRITIS, SYNOVIAL FLUID
in
Lancet
volume
2/8447
issue
8447
pages
127 - 128
publisher
Elsevier
external identifiers
  • Scopus:0021889712
language
English
LU publication?
yes
id
bc54368d-d6b3-41af-af8f-1d14aac3fa73
date added to LUP
2016-05-06 15:45:39
date last changed
2016-05-20 13:18:48
@misc{bc54368d-d6b3-41af-af8f-1d14aac3fa73,
  abstract     = {Cartilage proteoglycans were measured, by the use of an enzyme-linked immunosorbent assay, in synovial fluids obtained from 109 unselected patients attending an outpatient rheumatology clinic because of inflammation of the knee. The content of proteoglycans in synovial fluid was inversely related to the degree of joint destruction shown on X-ray. The proteoglycan concentrations in knee-joint exudates were higher in patients with reactive arthritis than in patients with rheumatoid arthritis having synovitis of corresponding duration and lacking radiological evidence of cartilage destruction. The measurement of proteoglycan levels may therefore be useful in differentiating between the two conditions.},
  author       = {Saxne, Tore and Heinegård, Dick and Wollheim, Frank and Petersson, H},
  keyword      = {CARTILAGE PROTEOGLYCAN ,RHEUMATOID ARTHRITIS,SYNOVIAL FLUID},
  language     = {eng},
  number       = {8447},
  pages        = {127--128},
  publisher    = {ARRAY(0xb6de830)},
  series       = {Lancet},
  title        = {Difference in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis.},
  volume       = {2/8447},
  year         = {1985},
}