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In Hypertrophic Cardiomyopathy, the Spatial Peaks QRS-T Angle Identifies Those With Sustained Ventricular Arrhythmias

Cortez, Daniel LU ; Graw, Sharon and Mestroni, Luisa (2016) In Clinical Cardiology 39(8). p.459-463
Abstract

Background: The spatial peaks QRS-T (SPQRS-T) angle differentiates hypertrophic cardiomyopathy (HCM) patients from controls. Increased angle confers arrhythmia risk in other populations. Hypothesis: We predict that the SPQRS-T angle will identify HCM patients with sustained ventricular arrhythmias (VAs) and those with New York Heart Association class III/IV heart failure. Methods: Corrected QT interval, QRS duration, and SPQRS-T angle were assessed in HCM patients with VAs (>30seconds) and those without VAs. Results: One hundred HCM patients (mean age, 32.7±17.2years) were assessed. Twenty patients had VAs. The corrected QT interval identified VA (P = 0.018) and at 460ms gave positive and negative predictive values of 28.6% and... (More)

Background: The spatial peaks QRS-T (SPQRS-T) angle differentiates hypertrophic cardiomyopathy (HCM) patients from controls. Increased angle confers arrhythmia risk in other populations. Hypothesis: We predict that the SPQRS-T angle will identify HCM patients with sustained ventricular arrhythmias (VAs) and those with New York Heart Association class III/IV heart failure. Methods: Corrected QT interval, QRS duration, and SPQRS-T angle were assessed in HCM patients with VAs (>30seconds) and those without VAs. Results: One hundred HCM patients (mean age, 32.7±17.2years) were assessed. Twenty patients had VAs. The corrected QT interval identified VA (P = 0.018) and at 460ms gave positive and negative predictive values of 28.6% and 83.3%, respectively, and an odds ratio of 2.0 (95% confidence interval: 0.7-5.6). The SPQRS-T angle differentiated VA from no VA (P <0.001) and at 124.1 degrees gave positive and negative predictive values and an odds ratio of 36.7%, 96.1%, and 14.2 (95% confidence interval: 3.1-65.6), respectively. Conclusions: The SPQRS-T angle best differentiated patients with VAs.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Cardiology
volume
39
issue
8
pages
459 - 463
publisher
Wiley-Blackwell
external identifiers
  • Scopus:84969916956
ISSN
0160-9289
DOI
10.1002/clc.22549
language
English
LU publication?
yes
id
c64f19cc-1329-4335-a735-12fca7865bc4
date added to LUP
2016-06-20 14:48:57
date last changed
2016-10-04 08:28:53
@misc{c64f19cc-1329-4335-a735-12fca7865bc4,
  abstract     = {<p>Background: The spatial peaks QRS-T (SPQRS-T) angle differentiates hypertrophic cardiomyopathy (HCM) patients from controls. Increased angle confers arrhythmia risk in other populations. Hypothesis: We predict that the SPQRS-T angle will identify HCM patients with sustained ventricular arrhythmias (VAs) and those with New York Heart Association class III/IV heart failure. Methods: Corrected QT interval, QRS duration, and SPQRS-T angle were assessed in HCM patients with VAs (&gt;30seconds) and those without VAs. Results: One hundred HCM patients (mean age, 32.7±17.2years) were assessed. Twenty patients had VAs. The corrected QT interval identified VA (P = 0.018) and at 460ms gave positive and negative predictive values of 28.6% and 83.3%, respectively, and an odds ratio of 2.0 (95% confidence interval: 0.7-5.6). The SPQRS-T angle differentiated VA from no VA (P &lt;0.001) and at 124.1 degrees gave positive and negative predictive values and an odds ratio of 36.7%, 96.1%, and 14.2 (95% confidence interval: 3.1-65.6), respectively. Conclusions: The SPQRS-T angle best differentiated patients with VAs.</p>},
  author       = {Cortez, Daniel and Graw, Sharon and Mestroni, Luisa},
  issn         = {0160-9289},
  language     = {eng},
  month        = {05},
  number       = {8},
  pages        = {459--463},
  publisher    = {ARRAY(0xb2560e0)},
  series       = {Clinical Cardiology},
  title        = {In Hypertrophic Cardiomyopathy, the Spatial Peaks QRS-T Angle Identifies Those With Sustained Ventricular Arrhythmias},
  url          = {http://dx.doi.org/10.1002/clc.22549},
  volume       = {39},
  year         = {2016},
}