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Dose response characteristics and basic dose distribution data for a polymerization-based dosemeter gel evaluated using MR

Haraldsson, P; Bäck, S A LU ; Magnusson, Peter LU and Olsson, L E LU (2000) In British Journal of Radiology 73(865). p.58-65
Abstract

A safe and reproducible mixing procedure for the manufacture of a polymerization-based dosemeter gel evaluated using MRI (PoMRI) is presented. The dose response, obtained by irradiating gel-filled vials with absorbed doses in the interval 0-20 Gy and evaluated with respect to 1/T2, was found to be linear in the interval 0-8 Gy, with a sensitivity of 0.211 s-1Gy-1 (r2 = 0.998) at 1.5 T. Evaluation of the same set of vials with respect to 1/T1 gave a sensitivity of 0.018 s-1Gy-1 (r2 = 0.960). PoMRI and diode data were compared for standard photon and electron treatment beams. A deviation of less than 3% was found between the two methods for central depth dose curves as well as dose profiles (2 mm for electrons in the steep dose gradient... (More)

A safe and reproducible mixing procedure for the manufacture of a polymerization-based dosemeter gel evaluated using MRI (PoMRI) is presented. The dose response, obtained by irradiating gel-filled vials with absorbed doses in the interval 0-20 Gy and evaluated with respect to 1/T2, was found to be linear in the interval 0-8 Gy, with a sensitivity of 0.211 s-1Gy-1 (r2 = 0.998) at 1.5 T. Evaluation of the same set of vials with respect to 1/T1 gave a sensitivity of 0.018 s-1Gy-1 (r2 = 0.960). PoMRI and diode data were compared for standard photon and electron treatment beams. A deviation of less than 3% was found between the two methods for central depth dose curves as well as dose profiles (2 mm for electrons in the steep dose gradient regions). The importance of the method used for background correction for the reliability of the results was also evaluated. Barex (with a wall thickness of 1.5 mm) was investigated for use as phantom material and found to be favourable compared with glass. The results obtained in this study show that PoMRI has excellent potential as a 3D detector.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Dose-Response Relationship, Radiation, Gels, Magnetic Resonance Imaging, Phantoms, Imaging, Polymers, Radiometry, Radiotherapy Dosage, Reproducibility of Results, Sensitivity and Specificity
in
British Journal of Radiology
volume
73
issue
865
pages
8 pages
publisher
British Inst Radiology
external identifiers
  • Scopus:17344383525
ISSN
0007-1285
DOI
10.1259/bjr.73.865.10721321
language
English
LU publication?
yes
id
e7a35284-5f57-45f3-b343-97d8af5c8086
date added to LUP
2016-08-16 12:14:17
date last changed
2016-10-13 05:12:18
@misc{e7a35284-5f57-45f3-b343-97d8af5c8086,
  abstract     = {<p>A safe and reproducible mixing procedure for the manufacture of a polymerization-based dosemeter gel evaluated using MRI (PoMRI) is presented. The dose response, obtained by irradiating gel-filled vials with absorbed doses in the interval 0-20 Gy and evaluated with respect to 1/T2, was found to be linear in the interval 0-8 Gy, with a sensitivity of 0.211 s-1Gy-1 (r2 = 0.998) at 1.5 T. Evaluation of the same set of vials with respect to 1/T1 gave a sensitivity of 0.018 s-1Gy-1 (r2 = 0.960). PoMRI and diode data were compared for standard photon and electron treatment beams. A deviation of less than 3% was found between the two methods for central depth dose curves as well as dose profiles (2 mm for electrons in the steep dose gradient regions). The importance of the method used for background correction for the reliability of the results was also evaluated. Barex (with a wall thickness of 1.5 mm) was investigated for use as phantom material and found to be favourable compared with glass. The results obtained in this study show that PoMRI has excellent potential as a 3D detector.</p>},
  author       = {Haraldsson, P and Bäck, S A and Magnusson, Peter and Olsson, L E},
  issn         = {0007-1285},
  keyword      = {Dose-Response Relationship, Radiation,Gels,Magnetic Resonance Imaging,Phantoms, Imaging,Polymers,Radiometry,Radiotherapy Dosage,Reproducibility of Results,Sensitivity and Specificity},
  language     = {eng},
  number       = {865},
  pages        = {58--65},
  publisher    = {ARRAY(0x783aad8)},
  series       = {British Journal of Radiology},
  title        = {Dose response characteristics and basic dose distribution data for a polymerization-based dosemeter gel evaluated using MR},
  url          = {http://dx.doi.org/10.1259/bjr.73.865.10721321},
  volume       = {73},
  year         = {2000},
}