Expression of brain-derived neurotrophic factor and of its functional receptor in neonatal and adult rat retina
(1995) In Neuroscience Letters 183(1-2). p.9-96- Abstract
The expression of mRNA coding for brain-derived neurotrophic factor (BDNF) and for its functional receptor, the full-length tyrosine kinase receptor trkB (trkB mRNA), was examined in early postnatal and adult rat retina by in situ hybridization using digoxygenin and radioactively-labeled oligonucleotide probes. BDNF and trkB mRNAs are expressed in the ganglion cell layer at postnatal-days (PN) 1, 4, 7, 14, 60, in proximal neuroblastic layer (PN 1, 4, 7), and proximal inner nuclear layer (PN 14, 60). Subpopulations of developing and mature retinal cells are thus capable of synthesizing BDNF.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/e9ad4675-f1ff-47e4-bb4b-1b473617ddfe
- author
- Perez, M T LU and Caminos, E
- organization
- publishing date
- 1995-01-02
- type
- Contribution to journal
- publication status
- published
- keywords
- Animals, Autoradiography, Brain-Derived Neurotrophic Factor, Gene Expression, Humans, In Situ Hybridization, Infant, Newborn, Nerve Tissue Proteins, RNA, Messenger, Rats, Rats, Sprague-Dawley, Receptors, Nerve Growth Factor, Retina, Journal Article, Research Support, Non-U.S. Gov't
- in
- Neuroscience Letters
- volume
- 183
- issue
- 1-2
- pages
- 9 - 96
- publisher
- Elsevier
- external identifiers
-
- scopus:0028855060
- pmid:7746496
- ISSN
- 0304-3940
- DOI
- 10.1016/0304-3940(94)11123-Z
- language
- English
- LU publication?
- yes
- id
- e9ad4675-f1ff-47e4-bb4b-1b473617ddfe
- date added to LUP
- 2016-10-27 19:33:42
- date last changed
- 2024-07-27 21:00:12
@article{e9ad4675-f1ff-47e4-bb4b-1b473617ddfe, abstract = {{<p>The expression of mRNA coding for brain-derived neurotrophic factor (BDNF) and for its functional receptor, the full-length tyrosine kinase receptor trkB (trkB mRNA), was examined in early postnatal and adult rat retina by in situ hybridization using digoxygenin and radioactively-labeled oligonucleotide probes. BDNF and trkB mRNAs are expressed in the ganglion cell layer at postnatal-days (PN) 1, 4, 7, 14, 60, in proximal neuroblastic layer (PN 1, 4, 7), and proximal inner nuclear layer (PN 14, 60). Subpopulations of developing and mature retinal cells are thus capable of synthesizing BDNF.</p>}}, author = {{Perez, M T and Caminos, E}}, issn = {{0304-3940}}, keywords = {{Animals; Autoradiography; Brain-Derived Neurotrophic Factor; Gene Expression; Humans; In Situ Hybridization; Infant, Newborn; Nerve Tissue Proteins; RNA, Messenger; Rats; Rats, Sprague-Dawley; Receptors, Nerve Growth Factor; Retina; Journal Article; Research Support, Non-U.S. Gov't}}, language = {{eng}}, month = {{01}}, number = {{1-2}}, pages = {{9--96}}, publisher = {{Elsevier}}, series = {{Neuroscience Letters}}, title = {{Expression of brain-derived neurotrophic factor and of its functional receptor in neonatal and adult rat retina}}, url = {{http://dx.doi.org/10.1016/0304-3940(94)11123-Z}}, doi = {{10.1016/0304-3940(94)11123-Z}}, volume = {{183}}, year = {{1995}}, }