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Leukemia

Juliusson, Gunnar LU and Hough, Rachael (2016) In Tumors in Adolescents and Young Adults 43. p.87-100
Abstract

Leukemias are a group of life threatening malignant disorders of the blood and bone marrow. In the adolescent and young adult (AYA) population, the acute leukemias are most prevalent, with chronic myeloid leukemia being infrequently seen. Factors associated with more aggressive disease biology tend to increase in frequency with increasing age, whilst tolerability of treatment strategies decreases. There are also challenges regarding the effective delivery of therapy specific to the AYA group, consequences on the unique psychosocial needs of this age group, including compliance. This chapter reviews the current status of epidemiology, pathophysiology, treatment strategies and outcomes of AYA leukemia, with a focus on acute lymphoblastic... (More)

Leukemias are a group of life threatening malignant disorders of the blood and bone marrow. In the adolescent and young adult (AYA) population, the acute leukemias are most prevalent, with chronic myeloid leukemia being infrequently seen. Factors associated with more aggressive disease biology tend to increase in frequency with increasing age, whilst tolerability of treatment strategies decreases. There are also challenges regarding the effective delivery of therapy specific to the AYA group, consequences on the unique psychosocial needs of this age group, including compliance. This chapter reviews the current status of epidemiology, pathophysiology, treatment strategies and outcomes of AYA leukemia, with a focus on acute lymphoblastic leukemia and acute myeloid leukemia.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
in
Tumors in Adolescents and Young Adults
editor
Stark, DP and Vassal, G
volume
43
pages
14 pages
publisher
S. Karger AG
external identifiers
  • Scopus:84987680552
ISBN
978-3-318-05911-3
DOI
10.1159/000447076
language
English
LU publication?
yes
id
f0bcaf16-ad3a-4dbd-8f1f-d6b31084d8cb
date added to LUP
2016-10-07 11:14:29
date last changed
2016-10-20 10:59:34
@misc{f0bcaf16-ad3a-4dbd-8f1f-d6b31084d8cb,
  abstract     = {<p>Leukemias are a group of life threatening malignant disorders of the blood and bone marrow. In the adolescent and young adult (AYA) population, the acute leukemias are most prevalent, with chronic myeloid leukemia being infrequently seen. Factors associated with more aggressive disease biology tend to increase in frequency with increasing age, whilst tolerability of treatment strategies decreases. There are also challenges regarding the effective delivery of therapy specific to the AYA group, consequences on the unique psychosocial needs of this age group, including compliance. This chapter reviews the current status of epidemiology, pathophysiology, treatment strategies and outcomes of AYA leukemia, with a focus on acute lymphoblastic leukemia and acute myeloid leukemia.</p>},
  author       = {Juliusson, Gunnar and Hough, Rachael},
  editor       = {Stark, DP and Vassal, G},
  isbn         = {978-3-318-05911-3 },
  language     = {eng},
  pages        = {87--100},
  publisher    = {ARRAY(0xb7b0bc8)},
  series       = {Tumors in Adolescents and Young Adults},
  title        = {Leukemia},
  url          = {http://dx.doi.org/10.1159/000447076},
  volume       = {43},
  year         = {2016},
}