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Segmentation of the Common Carotid Artery from Ultrasound Images using UNet

Friberg, Oskar LU (2020) BMEM01 20201
Department of Biomedical Engineering
Abstract
The common carotid artery (CCA), the artery that supplies our brains with oxygen, is of great importance in stroke research. The usual way to monitor the artery is by using ultrasound (US) imaging. An automated way of segmenting out the arteries from the US images is desired to optimize research. With an upswing in development of convolutional neural networks (CNN), this is now possible. CNN uses a training dataset to tweak a set of trainable parameters so that it can successfully classify images that is similar to the training data, and can then successfully segment out the CCA in new images.

However, the US images tend to have a large variation from patient to patient, since the artery and, the tissue and veins around the artery are... (More)
The common carotid artery (CCA), the artery that supplies our brains with oxygen, is of great importance in stroke research. The usual way to monitor the artery is by using ultrasound (US) imaging. An automated way of segmenting out the arteries from the US images is desired to optimize research. With an upswing in development of convolutional neural networks (CNN), this is now possible. CNN uses a training dataset to tweak a set of trainable parameters so that it can successfully classify images that is similar to the training data, and can then successfully segment out the CCA in new images.

However, the US images tend to have a large variation from patient to patient, since the artery and, the tissue and veins around the artery are not identical from patient to patient. A normal way that convolutional neural networks tackle this is by using a large training dataset to learn the variation, sadly a large dataset of out-segmented CCAs does not exist. This presents some challenges to using CNN to segment CCAs.

In this thesis, a case study has been performed with the fully convolutional neural network architecture called UNet, trained with less than 200 US images of the CCA to study if the network can segment the CCA in new images. With training data of around 200 US images, the network's output is compared to an expert's segmentation as the ground truth. The conclusion is that the network show promising result with an average of a 0.871 DICE similarity coefficient. Two key limitations were identified, first that images with a large difference in greyscale from the training data need to be preprocessed before, and secondly that artifacts need to be reduced to get a good segmentation.

The study does promote the use of UNet for segmenting the CCA in US images. With further development in postprocessing, a reliable way to segment the CCA in US images is possible. (Less)
Popular Abstract
UNet, a powerful tool for Ultrasound Image Analysis

Previously, deep learning for segmenting arteries in ultrasound images has been a big challenge. In this thesis, the newly developed convolutional neural network, UNet, was used to segment the main artery in our neck, the common carotid artery (CCA). The results show that UNet can be a powerful tool in image analysis within biomedical engineering.
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author
Friberg, Oskar LU
supervisor
organization
course
BMEM01 20201
year
type
H2 - Master's Degree (Two Years)
subject
keywords
MSc, Deep Learning, CNN, Computer Vision, Ultrasound, Carotid Artery
language
English
additional info
2020-03

Github for code: https://github.com/freeberg/ThesisOskarFriberg
id
9018213
date added to LUP
2020-06-15 12:45:34
date last changed
2020-06-15 12:45:34
@misc{9018213,
  abstract     = {{The common carotid artery (CCA), the artery that supplies our brains with oxygen, is of great importance in stroke research. The usual way to monitor the artery is by using ultrasound (US) imaging. An automated way of segmenting out the arteries from the US images is desired to optimize research. With an upswing in development of convolutional neural networks (CNN), this is now possible. CNN uses a training dataset to tweak a set of trainable parameters so that it can successfully classify images that is similar to the training data, and can then successfully segment out the CCA in new images.

However, the US images tend to have a large variation from patient to patient, since the artery and, the tissue and veins around the artery are not identical from patient to patient. A normal way that convolutional neural networks tackle this is by using a large training dataset to learn the variation, sadly a large dataset of out-segmented CCAs does not exist. This presents some challenges to using CNN to segment CCAs.

In this thesis, a case study has been performed with the fully convolutional neural network architecture called UNet, trained with less than 200 US images of the CCA to study if the network can segment the CCA in new images. With training data of around 200 US images, the network's output is compared to an expert's segmentation as the ground truth. The conclusion is that the network show promising result with an average of a 0.871 DICE similarity coefficient. Two key limitations were identified, first that images with a large difference in greyscale from the training data need to be preprocessed before, and secondly that artifacts need to be reduced to get a good segmentation.

The study does promote the use of UNet for segmenting the CCA in US images. With further development in postprocessing, a reliable way to segment the CCA in US images is possible.}},
  author       = {{Friberg, Oskar}},
  language     = {{eng}},
  note         = {{Student Paper}},
  title        = {{Segmentation of the Common Carotid Artery from Ultrasound Images using UNet}},
  year         = {{2020}},
}