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Quantification of Fetal Volume in Magnetic Resonance Images Using Deep Learning

Nilsson, Amanda LU (2021) In Master’s Theses in Mathematical Sciences FMAM05 20211
Mathematics (Faculty of Engineering)
Abstract
Background: Fetal Magnetic Resonance Imaging is an imaging technique that visualizes the fetus during pregnancy. It is used for assessing and diagnosing disease, for monitoring high risk pregnancies, and for conducting research. By segmenting three-dimensional fetal magnetic resonance (MR) images, volume estimation of intrauterine structures is possible. The quantification of fetal body volume and placental volume is of both clinical and scientific relevance. If performed manually, the segmentation is a time-consuming procedure.

Purpose: The aim of this project was to create a fully automatic algorithm that segments and quantifies the volumes of the fetus and placenta in MR images.

Method: Deep learning, or more specifically a... (More)
Background: Fetal Magnetic Resonance Imaging is an imaging technique that visualizes the fetus during pregnancy. It is used for assessing and diagnosing disease, for monitoring high risk pregnancies, and for conducting research. By segmenting three-dimensional fetal magnetic resonance (MR) images, volume estimation of intrauterine structures is possible. The quantification of fetal body volume and placental volume is of both clinical and scientific relevance. If performed manually, the segmentation is a time-consuming procedure.

Purpose: The aim of this project was to create a fully automatic algorithm that segments and quantifies the volumes of the fetus and placenta in MR images.

Method: Deep learning, or more specifically a two-dimensional U-Net, was used for solving the task. The data used for training, validation, and testing of the models were manually delineated volumetric MR images of 25 fetuses, which were considered as ground truth. In all images the fetus, placenta, umbilical cord and amniotic fluid were delineated. In addition to segmenting the fetus and placenta, the model was also trained to segment the umbilical cord and amniotic fluid.

Result: For the automatic fetal body volume the median absolute volume difference was 2.3 % (std 4.9 percentage points) for five cases that were used for testing, when compared to the ground truth. For the placental volume, the median absolute volume difference was instead 23.9 % (std 34.4 percentage points).

Conclusion: In conclusion, the results suggest that a fully automatic method based on the U-Net can be used for quantification of fetal body volume. However, the quantification of placental volume was not satisfactory. (Less)
Please use this url to cite or link to this publication:
author
Nilsson, Amanda LU
supervisor
organization
course
FMAM05 20211
year
type
H2 - Master's Degree (Two Years)
subject
keywords
MRI, Deep Learning, U-Net, Semantic segmentation, Fetal body volume, fetal MRI, Segmentation, Magnetic Resonance Imaging
publication/series
Master’s Theses in Mathematical Sciences
report number
LUTFMA-3439-2021
ISSN
1404-6342
other publication id
2021:E9
language
English
id
9043734
date added to LUP
2021-05-17 11:01:36
date last changed
2021-05-17 11:01:36
@misc{9043734,
  abstract     = {{Background: Fetal Magnetic Resonance Imaging is an imaging technique that visualizes the fetus during pregnancy. It is used for assessing and diagnosing disease, for monitoring high risk pregnancies, and for conducting research. By segmenting three-dimensional fetal magnetic resonance (MR) images, volume estimation of intrauterine structures is possible. The quantification of fetal body volume and placental volume is of both clinical and scientific relevance. If performed manually, the segmentation is a time-consuming procedure.

Purpose: The aim of this project was to create a fully automatic algorithm that segments and quantifies the volumes of the fetus and placenta in MR images.

Method: Deep learning, or more specifically a two-dimensional U-Net, was used for solving the task. The data used for training, validation, and testing of the models were manually delineated volumetric MR images of 25 fetuses, which were considered as ground truth. In all images the fetus, placenta, umbilical cord and amniotic fluid were delineated. In addition to segmenting the fetus and placenta, the model was also trained to segment the umbilical cord and amniotic fluid.

Result: For the automatic fetal body volume the median absolute volume difference was 2.3 % (std 4.9 percentage points) for five cases that were used for testing, when compared to the ground truth. For the placental volume, the median absolute volume difference was instead 23.9 % (std 34.4 percentage points).

Conclusion: In conclusion, the results suggest that a fully automatic method based on the U-Net can be used for quantification of fetal body volume. However, the quantification of placental volume was not satisfactory.}},
  author       = {{Nilsson, Amanda}},
  issn         = {{1404-6342}},
  language     = {{eng}},
  note         = {{Student Paper}},
  series       = {{Master’s Theses in Mathematical Sciences}},
  title        = {{Quantification of Fetal Volume in Magnetic Resonance Images Using Deep Learning}},
  year         = {{2021}},
}