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Topical corticosteroid phobia in atopic dermatitis : International feasibility study of the TOPICOP score

Stalder, J. F.; Aubert, H.; Anthoine, E.; Futamura, M.; Marcoux, D.; Morren, M. A.; Trzeciak, M.; Szalai, Z.; Veres, K. and Deleuran, M., et al. (2017) In Allergy: European Journal of Allergy and Clinical Immunology
Abstract

Background: Adherence to topical corticosteroids (TCS) is essential for the effective treatment of atopic dermatitis but can be limited by concerns about their use. This study examined the feasibility of applying the validated TOPICOP score for assessing TCS phobia across different countries. Methods: This was a prospective multicentre feasibility study conducted in 21 hospitals in 17 countries. Patients >3 months of age with atopic dermatitis or their parents or legal representatives completed a validated translation of the TOPICOP questionnaire in the country's native language. Respondents also completed questionnaires collecting opinions about the feasibility and acceptability of the TOPICOP questionnaire. Results: A total of 1564... (More)

Background: Adherence to topical corticosteroids (TCS) is essential for the effective treatment of atopic dermatitis but can be limited by concerns about their use. This study examined the feasibility of applying the validated TOPICOP score for assessing TCS phobia across different countries. Methods: This was a prospective multicentre feasibility study conducted in 21 hospitals in 17 countries. Patients >3 months of age with atopic dermatitis or their parents or legal representatives completed a validated translation of the TOPICOP questionnaire in the country's native language. Respondents also completed questionnaires collecting opinions about the feasibility and acceptability of the TOPICOP questionnaire. Results: A total of 1564 participants in 15 countries were included in the analysis. 81% of respondents considered the questions clear or very clear, and 79% reported that it took less than 5 minutes to complete. Each of the individual items in the TOPICOP questionnaire was considered to be not at all difficult to answer by 49% to 74% of participants. The mean global TOPICOP score was 44.7%±20.5. Mean TOPICOP subscores were 37.0±22.8% for knowledge and beliefs, 54.7±27.8% for fears and 50.1±29.1% for behaviours. Global scores and subscores differed between countries, although the subscores did not always vary in parallel, suggesting different levels of TCS phobia and different drivers for each country. Conclusions: The TOPICOP score can be feasibly applied across countries and may therefore be useful for obtaining qualitative and quantitative data from international studies and for adapting patient education and treatment.

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publication status
epub
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keywords
Adherence, Atopic dermatitis, Corticosteroid
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Allergy: European Journal of Allergy and Clinical Immunology
publisher
Wiley-Blackwell
external identifiers
  • scopus:85019941555
ISSN
0105-4538
DOI
10.1111/all.13189
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English
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0000d9ef-fc46-4506-8131-fc7b2107727c
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2017-06-26 14:33:50
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2018-01-07 12:09:06
@article{0000d9ef-fc46-4506-8131-fc7b2107727c,
  abstract     = {<p>Background: Adherence to topical corticosteroids (TCS) is essential for the effective treatment of atopic dermatitis but can be limited by concerns about their use. This study examined the feasibility of applying the validated TOPICOP score for assessing TCS phobia across different countries. Methods: This was a prospective multicentre feasibility study conducted in 21 hospitals in 17 countries. Patients &gt;3 months of age with atopic dermatitis or their parents or legal representatives completed a validated translation of the TOPICOP questionnaire in the country's native language. Respondents also completed questionnaires collecting opinions about the feasibility and acceptability of the TOPICOP questionnaire. Results: A total of 1564 participants in 15 countries were included in the analysis. 81% of respondents considered the questions clear or very clear, and 79% reported that it took less than 5 minutes to complete. Each of the individual items in the TOPICOP questionnaire was considered to be not at all difficult to answer by 49% to 74% of participants. The mean global TOPICOP score was 44.7%±20.5. Mean TOPICOP subscores were 37.0±22.8% for knowledge and beliefs, 54.7±27.8% for fears and 50.1±29.1% for behaviours. Global scores and subscores differed between countries, although the subscores did not always vary in parallel, suggesting different levels of TCS phobia and different drivers for each country. Conclusions: The TOPICOP score can be feasibly applied across countries and may therefore be useful for obtaining qualitative and quantitative data from international studies and for adapting patient education and treatment.</p>},
  author       = {Stalder, J. F. and Aubert, H. and Anthoine, E. and Futamura, M. and Marcoux, D. and Morren, M. A. and Trzeciak, M. and Szalai, Z. and Veres, K. and Deleuran, M. and Vestergaard, C. and Boralevi, F and Chu, C. Y. and De Raeve, L and Svensson, A. and Fölster-Holst, R. and Buchner, M and Takaoka, R. and Aoki, V. and Chernyshov, P. and Chernyshova, L. and Murrell, Dedee F. and Zhao, C. and Mckinster, C. D. and Von Kobyletzky, L. and Eichenfield, L. F. and Totri, C. and Lio, P. and Seneschal, J. and Moret, L. and Barbarot, S},
  issn         = {0105-4538},
  keyword      = {Adherence,Atopic dermatitis,Corticosteroid},
  language     = {eng},
  publisher    = {Wiley-Blackwell},
  series       = {Allergy: European Journal of Allergy and Clinical Immunology},
  title        = {Topical corticosteroid phobia in atopic dermatitis : International feasibility study of the TOPICOP score},
  url          = {http://dx.doi.org/10.1111/all.13189},
  year         = {2017},
}