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MNS and Duffy Blood Group Systems

Storry, Jill R. LU (2024) p.127-130
Abstract

The MNS blood group system antigens (M, N, S, s, U, and other high- and low-frequency antigens) are carried on glycophorins A and B, or hybrid proteins thereof. Antibodies to these antigens can be clinically significant, especially anti-S, anti-s, and anti-U. The Duffy blood group system antigens (Fya, Fyb, Fy3) are carried on the atypical chemokine receptor 1 (ACKR1). Antibodies to the Duffy antigens are clinically significant. Both the glycophorins and Duffy play a role in resistance to malaria.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
ACKR1, Blood group antigen, Chemokine receptor, Duffy blood group, Erythrocyte, Glycophorin, Malaria, MNS blood group
host publication
Transfusion Medicine and Hemostasis : Clinical and Laboratory Aspects - Clinical and Laboratory Aspects
edition
4th
pages
4 pages
publisher
Elsevier
external identifiers
  • scopus:85213172967
ISBN
9780323960144
9780323960151
DOI
10.1016/B978-0-323-96014-4.00015-X
language
English
LU publication?
yes
id
0041f867-c447-4492-b93d-024846ccc8bd
date added to LUP
2025-01-24 14:12:22
date last changed
2025-06-14 01:00:37
@inbook{0041f867-c447-4492-b93d-024846ccc8bd,
  abstract     = {{<p>The MNS blood group system antigens (M, N, S, s, U, and other high- and low-frequency antigens) are carried on glycophorins A and B, or hybrid proteins thereof. Antibodies to these antigens can be clinically significant, especially anti-S, anti-s, and anti-U. The Duffy blood group system antigens (Fya, Fyb, Fy3) are carried on the atypical chemokine receptor 1 (ACKR1). Antibodies to the Duffy antigens are clinically significant. Both the glycophorins and Duffy play a role in resistance to malaria.</p>}},
  author       = {{Storry, Jill R.}},
  booktitle    = {{Transfusion Medicine and Hemostasis : Clinical and Laboratory Aspects}},
  isbn         = {{9780323960144}},
  keywords     = {{ACKR1; Blood group antigen; Chemokine receptor; Duffy blood group; Erythrocyte; Glycophorin; Malaria; MNS blood group}},
  language     = {{eng}},
  pages        = {{127--130}},
  publisher    = {{Elsevier}},
  title        = {{MNS and Duffy Blood Group Systems}},
  url          = {{http://dx.doi.org/10.1016/B978-0-323-96014-4.00015-X}},
  doi          = {{10.1016/B978-0-323-96014-4.00015-X}},
  year         = {{2024}},
}