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Contact Allergy to Allergens in the Swedish Baseline Series Over-represented in Diabetes Patients with Skin Reactions to Medical Devices : A Retrospective Study from Southern Sweden

Ulriksdotter, Josefin LU orcid ; Sukakul, Thanisorn LU orcid ; Bruze, Magnus LU ; Mowitz, Martin LU ; Ofenloch, Robert and Svedman, Cecilia LU (2024) In Acta Dermato-Venereologica 104.
Abstract

Allergic contact dermatitis is reported among individuals using continuous glucose monitoring systems and insulin pumps. The aim of this study was to describe contact allergy patterns for allergens in the Swedish baseline series and medical device-related allergens among users. Contact allergy to baseline series allergens and isobornyl acrylate was compared between diabetes patients and dermatitis patients patch-tested at the Department of Occupational and Environmental Dermatology during 2017 to 2020. Fifty-four diabetes patients and 2,567 dermatitis patients were included. The prevalence of contact allergy to fragrance mix II and sesquiterpene lactone mix was significantly higher in diabetes patients compared with dermatitis patients.... (More)

Allergic contact dermatitis is reported among individuals using continuous glucose monitoring systems and insulin pumps. The aim of this study was to describe contact allergy patterns for allergens in the Swedish baseline series and medical device-related allergens among users. Contact allergy to baseline series allergens and isobornyl acrylate was compared between diabetes patients and dermatitis patients patch-tested at the Department of Occupational and Environmental Dermatology during 2017 to 2020. Fifty-four diabetes patients and 2,567 dermatitis patients were included. The prevalence of contact allergy to fragrance mix II and sesquiterpene lactone mix was significantly higher in diabetes patients compared with dermatitis patients. Of the diabetes patients 13.0% and of the dermatitis patients 0.5% tested positive to sesquiterpene lactone mix (p < 0.001). Of the diabetes patients 7.4% and of the dermatitis patients 2.3% tested positive to fragrance mix II (p = 0.041). Of the diabetes patients 70.4% tested positive to medical de-vice-related allergens. Of the diabetes patients 63.0% and of the dermatitis patients 0.2% were allergic to isobornyl acrylate (p < 0.001). In conclusion, not only medical device-related contact allergies, but also contact allergy to baseline series allergens (fragrance mix II and sesquiterpene lactone mix), is overrepresented in diabetes patients who use medical devices.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
allergic contact dermatitis, continuous glucose monitoring, diabetes type 1, insulin pump, isobornyl acrylate, patch-testing
in
Acta Dermato-Venereologica
volume
104
article number
adv19676
publisher
Medical Journals Limited
external identifiers
  • scopus:85189277881
  • pmid:38551376
ISSN
0001-5555
DOI
10.2340/actadv.v104.19676
language
English
LU publication?
yes
id
008d684f-9fb8-46a0-9b0e-f5ccca005efa
date added to LUP
2024-04-22 15:20:39
date last changed
2024-06-17 20:17:00
@article{008d684f-9fb8-46a0-9b0e-f5ccca005efa,
  abstract     = {{<p>Allergic contact dermatitis is reported among individuals using continuous glucose monitoring systems and insulin pumps. The aim of this study was to describe contact allergy patterns for allergens in the Swedish baseline series and medical device-related allergens among users. Contact allergy to baseline series allergens and isobornyl acrylate was compared between diabetes patients and dermatitis patients patch-tested at the Department of Occupational and Environmental Dermatology during 2017 to 2020. Fifty-four diabetes patients and 2,567 dermatitis patients were included. The prevalence of contact allergy to fragrance mix II and sesquiterpene lactone mix was significantly higher in diabetes patients compared with dermatitis patients. Of the diabetes patients 13.0% and of the dermatitis patients 0.5% tested positive to sesquiterpene lactone mix (p &lt; 0.001). Of the diabetes patients 7.4% and of the dermatitis patients 2.3% tested positive to fragrance mix II (p = 0.041). Of the diabetes patients 70.4% tested positive to medical de-vice-related allergens. Of the diabetes patients 63.0% and of the dermatitis patients 0.2% were allergic to isobornyl acrylate (p &lt; 0.001). In conclusion, not only medical device-related contact allergies, but also contact allergy to baseline series allergens (fragrance mix II and sesquiterpene lactone mix), is overrepresented in diabetes patients who use medical devices.</p>}},
  author       = {{Ulriksdotter, Josefin and Sukakul, Thanisorn and Bruze, Magnus and Mowitz, Martin and Ofenloch, Robert and Svedman, Cecilia}},
  issn         = {{0001-5555}},
  keywords     = {{allergic contact dermatitis; continuous glucose monitoring; diabetes type 1; insulin pump; isobornyl acrylate; patch-testing}},
  language     = {{eng}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Contact Allergy to Allergens in the Swedish Baseline Series Over-represented in Diabetes Patients with Skin Reactions to Medical Devices : A Retrospective Study from Southern Sweden}},
  url          = {{http://dx.doi.org/10.2340/actadv.v104.19676}},
  doi          = {{10.2340/actadv.v104.19676}},
  volume       = {{104}},
  year         = {{2024}},
}