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Imaging biomarkers of dementia : recommended visual rating scales with teaching cases

Wahlund, Lars -Olof; Westman, Eric; van Westen, Danielle LU ; Wallin, Anders; Shams, Sara; Cavallin, Lena and Larsson, Elna Marie (2017) In Insights into Imaging 8(1). p.79-90
Abstract

Abstract: The diagnostic work up of dementia may benefit from structured reporting of CT and/or MRI and the use of standardised visual rating scales. We advocate a more widespread use of standardised scales as part of the workflow in clinical and research evaluation of dementia. We propose routine clinical use of rating scales for medial temporal atrophy (MTA), global cortical atrophy (GCA) and white matter hyperintensities (WMH). These scales can be used for evaluation of both CT and MRI and are efficient in routine imaging assessment in dementia, and may improve the accuracy of diagnosis. Our review provides detailed imaging examples of rating increments in each of these scales and a separate teaching file. The radiologist should... (More)

Abstract: The diagnostic work up of dementia may benefit from structured reporting of CT and/or MRI and the use of standardised visual rating scales. We advocate a more widespread use of standardised scales as part of the workflow in clinical and research evaluation of dementia. We propose routine clinical use of rating scales for medial temporal atrophy (MTA), global cortical atrophy (GCA) and white matter hyperintensities (WMH). These scales can be used for evaluation of both CT and MRI and are efficient in routine imaging assessment in dementia, and may improve the accuracy of diagnosis. Our review provides detailed imaging examples of rating increments in each of these scales and a separate teaching file. The radiologist should relate visual ratings to the clinical assessment and other biomarkers to assist the clinician in the diagnostic decision. Teaching points: • Clinical dementia diagnostics would benefit from structured radiological reporting. • Standardised rating scales should be used in dementia assessment. • It is important to relate imaging findings to the clinically suspected diagnosis.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Alzheimer’s disease, CT, Dementia, Imaging, MRI
in
Insights into Imaging
volume
8
issue
1
pages
12 pages
publisher
Springer
external identifiers
  • scopus:85010680210
  • wos:000397245200008
ISSN
1869-4101
DOI
10.1007/s13244-016-0521-6
language
English
LU publication?
yes
id
00aa4604-0e9c-472c-8aa8-97430fdedcbc
date added to LUP
2017-02-14 12:31:05
date last changed
2018-06-03 04:53:51
@article{00aa4604-0e9c-472c-8aa8-97430fdedcbc,
  abstract     = {<p>Abstract: The diagnostic work up of dementia may benefit from structured reporting of CT and/or MRI and the use of standardised visual rating scales. We advocate a more widespread use of standardised scales as part of the workflow in clinical and research evaluation of dementia. We propose routine clinical use of rating scales for medial temporal atrophy (MTA), global cortical atrophy (GCA) and white matter hyperintensities (WMH). These scales can be used for evaluation of both CT and MRI and are efficient in routine imaging assessment in dementia, and may improve the accuracy of diagnosis. Our review provides detailed imaging examples of rating increments in each of these scales and a separate teaching file. The radiologist should relate visual ratings to the clinical assessment and other biomarkers to assist the clinician in the diagnostic decision. Teaching points: • Clinical dementia diagnostics would benefit from structured radiological reporting. • Standardised rating scales should be used in dementia assessment. • It is important to relate imaging findings to the clinically suspected diagnosis.</p>},
  author       = {Wahlund, Lars -Olof and Westman, Eric and van Westen, Danielle and Wallin, Anders and Shams, Sara and Cavallin, Lena and Larsson, Elna Marie},
  issn         = {1869-4101},
  keyword      = {Alzheimer’s disease,CT,Dementia,Imaging,MRI},
  language     = {eng},
  month        = {02},
  number       = {1},
  pages        = {79--90},
  publisher    = {Springer},
  series       = {Insights into Imaging},
  title        = {Imaging biomarkers of dementia : recommended visual rating scales with teaching cases},
  url          = {http://dx.doi.org/10.1007/s13244-016-0521-6},
  volume       = {8},
  year         = {2017},
}