Advanced

Migrating birds rapidly increase constitutive immune function during stopover

Eikenaar, Cas ; Hessler, Sven and Hegemann, Arne LU (2020) In Royal Society Open Science 7(2).
Abstract

Migratory flight is physiologically highly demanding and has been shown to negatively affect multiple parameters of constitutive immune function (CIF), an animal’s first line of physiological defence against infections. In between migratory flights, most birds make stopovers, periods during which they accumulate fuel for the next flight(s). Stopovers are also commonly thought of as periods of rest and recovery, but what this encompasses is largely undefined. Here, we show that during stopover, northern wheatears Oenanthe oenanthe, a long-distance migratory bird, can rapidly increase constitutive innate immune function. We caught and temporarily caged birds under ad libitum food conditions at a stopover site in autumn. Within 2 days,... (More)

Migratory flight is physiologically highly demanding and has been shown to negatively affect multiple parameters of constitutive immune function (CIF), an animal’s first line of physiological defence against infections. In between migratory flights, most birds make stopovers, periods during which they accumulate fuel for the next flight(s). Stopovers are also commonly thought of as periods of rest and recovery, but what this encompasses is largely undefined. Here, we show that during stopover, northern wheatears Oenanthe oenanthe, a long-distance migratory bird, can rapidly increase constitutive innate immune function. We caught and temporarily caged birds under ad libitum food conditions at a stopover site in autumn. Within 2 days, most birds significantly increased complement activity and their ability to kill microbes. Changes in immune function were not related to the birds’ food intake or extent of fuel accumulation. Our study suggests that stopovers may not only be important to refuel but also to restore immune function. Additionally, the increase in CIF could help migrating birds to deal with novel pathogens they may encounter at stopover sites.

(Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Avian, Eco-immunology, Immunity, Longitudinal (within-individual) data, Migration, Recovery
in
Royal Society Open Science
volume
7
issue
2
article number
192031
publisher
Royal Society
external identifiers
  • pmid:32257353
  • scopus:85081586523
ISSN
2054-5703
DOI
10.1098/rsos.192031
language
English
LU publication?
yes
id
00f101c0-a73d-4a0f-aaef-ef8e58257930
date added to LUP
2020-04-07 14:10:09
date last changed
2020-07-08 03:00:39
@article{00f101c0-a73d-4a0f-aaef-ef8e58257930,
  abstract     = {<p>Migratory flight is physiologically highly demanding and has been shown to negatively affect multiple parameters of constitutive immune function (CIF), an animal’s first line of physiological defence against infections. In between migratory flights, most birds make stopovers, periods during which they accumulate fuel for the next flight(s). Stopovers are also commonly thought of as periods of rest and recovery, but what this encompasses is largely undefined. Here, we show that during stopover, northern wheatears Oenanthe oenanthe, a long-distance migratory bird, can rapidly increase constitutive innate immune function. We caught and temporarily caged birds under ad libitum food conditions at a stopover site in autumn. Within 2 days, most birds significantly increased complement activity and their ability to kill microbes. Changes in immune function were not related to the birds’ food intake or extent of fuel accumulation. Our study suggests that stopovers may not only be important to refuel but also to restore immune function. Additionally, the increase in CIF could help migrating birds to deal with novel pathogens they may encounter at stopover sites.</p>},
  author       = {Eikenaar, Cas and Hessler, Sven and Hegemann, Arne},
  issn         = {2054-5703},
  language     = {eng},
  month        = {02},
  number       = {2},
  publisher    = {Royal Society},
  series       = {Royal Society Open Science},
  title        = {Migrating birds rapidly increase constitutive immune function during stopover},
  url          = {http://dx.doi.org/10.1098/rsos.192031},
  doi          = {10.1098/rsos.192031},
  volume       = {7},
  year         = {2020},
}