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Pencil beam scanning proton therapy of Hodgkin’s lymphoma in deep inspiration breath-hold: a case series report

Andersson, Karin ; Edvardsson, Anneli LU ; Hall, Annika ; Enmark, Marika and Fagerström Kristensen, Ingrid LU (2019) In Technical Innovations and Patient Support in Radiation Oncology 13. p.6-10
Abstract
Background
Most patients with Hodgkin’s lymphoma are young and have a favourable prognosis, therefore it is of high importance to decrease the radiation doses to normal tissues received during radiotherapy. A combination of proton therapy and deep inspiration breath-hold technique (DIBH) can improve the sparing effect and thereby reduce the risk of late effects.

Case presentation
The two first patient cases treated with proton therapy in DIBH at the Skandion Clinic, Uppsala, Sweden, are presented here. Proton treatment plans were compared to photon plans based on doses to target and organs at risk. Several CT scans were acquired during the treatment course and inter breath-hold variations were evaluated based on anatomical... (More)
Background
Most patients with Hodgkin’s lymphoma are young and have a favourable prognosis, therefore it is of high importance to decrease the radiation doses to normal tissues received during radiotherapy. A combination of proton therapy and deep inspiration breath-hold technique (DIBH) can improve the sparing effect and thereby reduce the risk of late effects.

Case presentation
The two first patient cases treated with proton therapy in DIBH at the Skandion Clinic, Uppsala, Sweden, are presented here. Proton treatment plans were compared to photon plans based on doses to target and organs at risk. Several CT scans were acquired during the treatment course and inter breath-hold variations were evaluated based on anatomical distances and dosimetric comparisons.

Conclusions
The results from our first patients treated with proton therapy in DIBH imply that the treatment strategy is robust and has the potential to reduce dose to normal tissue.

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author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Technical Innovations and Patient Support in Radiation Oncology
volume
13
pages
6 - 10
publisher
Elsevier
external identifiers
  • scopus:85105118585
ISSN
2405-6324
DOI
10.1016/j.tipsro.2019.11.006
language
English
LU publication?
no
id
00f3fd49-9c43-4480-aff1-ba78ecded07e
date added to LUP
2023-01-09 14:15:24
date last changed
2023-01-14 04:05:28
@article{00f3fd49-9c43-4480-aff1-ba78ecded07e,
  abstract     = {{Background<br/>Most patients with Hodgkin’s lymphoma are young and have a favourable prognosis, therefore it is of high importance to decrease the radiation doses to normal tissues received during radiotherapy. A combination of proton therapy and deep inspiration breath-hold technique (DIBH) can improve the sparing effect and thereby reduce the risk of late effects.<br/><br/>Case presentation<br/>The two first patient cases treated with proton therapy in DIBH at the Skandion Clinic, Uppsala, Sweden, are presented here. Proton treatment plans were compared to photon plans based on doses to target and organs at risk. Several CT scans were acquired during the treatment course and inter breath-hold variations were evaluated based on anatomical distances and dosimetric comparisons.<br/><br/>Conclusions<br/>The results from our first patients treated with proton therapy in DIBH imply that the treatment strategy is robust and has the potential to reduce dose to normal tissue.<br/><br/>}},
  author       = {{Andersson, Karin and Edvardsson, Anneli and Hall, Annika and Enmark, Marika and Fagerström Kristensen, Ingrid}},
  issn         = {{2405-6324}},
  language     = {{eng}},
  pages        = {{6--10}},
  publisher    = {{Elsevier}},
  series       = {{Technical Innovations and Patient Support in Radiation Oncology}},
  title        = {{Pencil beam scanning proton therapy of Hodgkin’s lymphoma in deep inspiration breath-hold: a case series report}},
  url          = {{http://dx.doi.org/10.1016/j.tipsro.2019.11.006}},
  doi          = {{10.1016/j.tipsro.2019.11.006}},
  volume       = {{13}},
  year         = {{2019}},
}