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Swedish guidelines for device-aided therapies in Parkinson's disease —Economic evaluation and implementation

Norlin, Jenny M. ; Willis, Michael ; Persson, Ulf ; Andersson, Emelie ; E. Pålhagen, Sven LU and Odin, Per LU orcid (2021) In Acta Neurologica Scandinavica 144(2). p.170-178
Abstract

Objectives: The National Board of Health and Welfare in Sweden published the national guidelines for Parkinson's Disease 2016. The aim of this study was to summarize this evidence review and development of the guidelines, focusing on the economic evaluation of device-aided therapies (deep brain stimulation, pump-based infusion of levodopa-carbidopa intestinal gel or apomorphine) for Parkinson's disease, and the rate of implementation after 3 years in Sweden. Material and methods: The evidence review underlying the guidelines—including systematic literature searches of clinical and economic evidence, model-based economic evaluation, and formal analysis and guideline development—was examined, condensed, and translated. The impact of the... (More)

Objectives: The National Board of Health and Welfare in Sweden published the national guidelines for Parkinson's Disease 2016. The aim of this study was to summarize this evidence review and development of the guidelines, focusing on the economic evaluation of device-aided therapies (deep brain stimulation, pump-based infusion of levodopa-carbidopa intestinal gel or apomorphine) for Parkinson's disease, and the rate of implementation after 3 years in Sweden. Material and methods: The evidence review underlying the guidelines—including systematic literature searches of clinical and economic evidence, model-based economic evaluation, and formal analysis and guideline development—was examined, condensed, and translated. The impact of the guidelines was assessed with treatment use statistics from 2009 to 2019. Results: All device-aided therapies were assigned high priority. Based on a relatively low proportion of device-aided therapies (30%) in Parkinson's disease, a 5-year increase of 500 patients was recommended. This was estimated to reduce total costs by SEK 14 million (€1.7 million). Follow-up data found an increase of 217 patients between 2017 and 2019, following the same trend as before the guidelines. Conclusion: Three years after the guidelines were published, the use of device-aided therapies has increased in Sweden, albeit not in pace with recommendations. One reason for slow implementation may be poor incentivization related to budget silos in which the costs for device-aided therapies are borne by the regions but the cost offsets (eg, reduced need for home care) are reaped by local stakeholders.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
National Guidelines, Parkinson's disease, Sweden, ​Cost-effectiveness, ​Device-​Aided ​Therapies, ​Economic model, ​Literature review
in
Acta Neurologica Scandinavica
volume
144
issue
2
pages
170 - 178
publisher
Wiley-Blackwell
external identifiers
  • scopus:85104877082
  • pmid:33899213
ISSN
0001-6314
DOI
10.1111/ane.13434
language
English
LU publication?
yes
id
013e5d27-4b6e-468d-b826-5c15311370d7
date added to LUP
2021-05-12 17:12:12
date last changed
2024-06-15 11:10:09
@article{013e5d27-4b6e-468d-b826-5c15311370d7,
  abstract     = {{<p>Objectives: The National Board of Health and Welfare in Sweden published the national guidelines for Parkinson's Disease 2016. The aim of this study was to summarize this evidence review and development of the guidelines, focusing on the economic evaluation of device-aided therapies (deep brain stimulation, pump-based infusion of levodopa-carbidopa intestinal gel or apomorphine) for Parkinson's disease, and the rate of implementation after 3 years in Sweden. Material and methods: The evidence review underlying the guidelines—including systematic literature searches of clinical and economic evidence, model-based economic evaluation, and formal analysis and guideline development—was examined, condensed, and translated. The impact of the guidelines was assessed with treatment use statistics from 2009 to 2019. Results: All device-aided therapies were assigned high priority. Based on a relatively low proportion of device-aided therapies (30%) in Parkinson's disease, a 5-year increase of 500 patients was recommended. This was estimated to reduce total costs by SEK 14 million (€1.7 million). Follow-up data found an increase of 217 patients between 2017 and 2019, following the same trend as before the guidelines. Conclusion: Three years after the guidelines were published, the use of device-aided therapies has increased in Sweden, albeit not in pace with recommendations. One reason for slow implementation may be poor incentivization related to budget silos in which the costs for device-aided therapies are borne by the regions but the cost offsets (eg, reduced need for home care) are reaped by local stakeholders.</p>}},
  author       = {{Norlin, Jenny M. and Willis, Michael and Persson, Ulf and Andersson, Emelie and E. Pålhagen, Sven and Odin, Per}},
  issn         = {{0001-6314}},
  keywords     = {{National Guidelines; Parkinson's disease; Sweden; ​Cost-effectiveness; ​Device-​Aided ​Therapies; ​Economic model; ​Literature review}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{170--178}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Neurologica Scandinavica}},
  title        = {{Swedish guidelines for device-aided therapies in Parkinson's disease —Economic evaluation and implementation}},
  url          = {{http://dx.doi.org/10.1111/ane.13434}},
  doi          = {{10.1111/ane.13434}},
  volume       = {{144}},
  year         = {{2021}},
}