Changes in transport functions of isolated rabbit choroid plexus under the influence of oestrogen and progesterone
(1989) In Acta Physiologica Scandinavica 136(1). p.107-111- Abstract
- Isolated choroid plexuses from rabbits were used to determine uptake and accumulation of 10(-5) M radiolabelled choline (expressed as tissue/medium ratio) and the activities of various types of ATPases (based on ouabain inhibition and bicarbonate stimulation) following pre-treatment of the animals with 0.5 mg kg-1 17-beta-oestradiol, alone or in combination with 2 mg kg-1 progesterone. The combined treatment reduced the choline uptake by 35% and also lowered the activity of Na+,K+-ATPase by 31%, without influencing tissue wet weight. The reduction in HCO3-ATPase was smaller and not statistically significant. There was a tendency also for oestrogen alone to lower these activities, but only by less than 20%. The Ca2+,Mg2+-ATPase activity was... (More)
- Isolated choroid plexuses from rabbits were used to determine uptake and accumulation of 10(-5) M radiolabelled choline (expressed as tissue/medium ratio) and the activities of various types of ATPases (based on ouabain inhibition and bicarbonate stimulation) following pre-treatment of the animals with 0.5 mg kg-1 17-beta-oestradiol, alone or in combination with 2 mg kg-1 progesterone. The combined treatment reduced the choline uptake by 35% and also lowered the activity of Na+,K+-ATPase by 31%, without influencing tissue wet weight. The reduction in HCO3-ATPase was smaller and not statistically significant. There was a tendency also for oestrogen alone to lower these activities, but only by less than 20%. The Ca2+,Mg2+-ATPase activity was not significantly affected by any of the hormones. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1104683
- author
- Lindvall-Axelsson, M and Owman, Christer LU
- organization
- publishing date
- 1989
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Physiologica Scandinavica
- volume
- 136
- issue
- 1
- pages
- 107 - 111
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:2549764
- scopus:0024660670
- ISSN
- 0001-6772
- language
- English
- LU publication?
- yes
- id
- 01c141b3-7fdc-4b08-b7d2-78d2f4d12263 (old id 1104683)
- date added to LUP
- 2016-04-01 16:22:03
- date last changed
- 2021-01-03 07:07:51
@article{01c141b3-7fdc-4b08-b7d2-78d2f4d12263, abstract = {{Isolated choroid plexuses from rabbits were used to determine uptake and accumulation of 10(-5) M radiolabelled choline (expressed as tissue/medium ratio) and the activities of various types of ATPases (based on ouabain inhibition and bicarbonate stimulation) following pre-treatment of the animals with 0.5 mg kg-1 17-beta-oestradiol, alone or in combination with 2 mg kg-1 progesterone. The combined treatment reduced the choline uptake by 35% and also lowered the activity of Na+,K+-ATPase by 31%, without influencing tissue wet weight. The reduction in HCO3-ATPase was smaller and not statistically significant. There was a tendency also for oestrogen alone to lower these activities, but only by less than 20%. The Ca2+,Mg2+-ATPase activity was not significantly affected by any of the hormones.}}, author = {{Lindvall-Axelsson, M and Owman, Christer}}, issn = {{0001-6772}}, language = {{eng}}, number = {{1}}, pages = {{107--111}}, publisher = {{Wiley-Blackwell}}, series = {{Acta Physiologica Scandinavica}}, title = {{Changes in transport functions of isolated rabbit choroid plexus under the influence of oestrogen and progesterone}}, volume = {{136}}, year = {{1989}}, }