Exposure to dioxins as a risk factor for soft tissue sarcoma : A population - based case-control study
Eriksson, Mikael LU
; Hardell, Lennart
and Adami, Hans Olov
(1990)
In Journal of the National Cancer Institute
82(6).
p.486-490
- Abstract
In a case-control study including 237 cases with soft tissue sarcoma and 237 controls, previous jobs and exposures to different agents, including pesticides, were assessed. Exposure to phenoxyacetic acids or chlorophenols gave a statistically significant increased rate ratio (RR) of 1.80 [95% confidence interval (CI) = 1.02-3.18] for soft tissue sarcoma. Exposure to phenoxyacetic acids of all types gave a nonsignificantly increased RR of 1.34 (95% CI = 0.70-2.56). During the 1950s, exposure to 2,4,5-trichlorophenoxyacetic acid gave a threefold significantly increased risk. High-grade exposure to chlorophenols, which are also contaminated by dioxins, gave an RR of 5.25 (95% CI = 1.69-16.34). The increased risk was thus attributed to... (More)
In a case-control study including 237 cases with soft tissue sarcoma and 237 controls, previous jobs and exposures to different agents, including pesticides, were assessed. Exposure to phenoxyacetic acids or chlorophenols gave a statistically significant increased rate ratio (RR) of 1.80 [95% confidence interval (CI) = 1.02-3.18] for soft tissue sarcoma. Exposure to phenoxyacetic acids of all types gave a nonsignificantly increased RR of 1.34 (95% CI = 0.70-2.56). During the 1950s, exposure to 2,4,5-trichlorophenoxyacetic acid gave a threefold significantly increased risk. High-grade exposure to chlorophenols, which are also contaminated by dioxins, gave an RR of 5.25 (95% CI = 1.69-16.34). The increased risk was thus attributed to dioxin-contaminated phenoxy-acetic acids or chlorophenols that gave an RR of 2.43 (95% CI = 1.30-4.54). [J Natl Cancer Inst 82:486-490, 1990].
(Less)
- author
- Eriksson, Mikael
LU
; Hardell, Lennart
and Adami, Hans Olov
- publishing date
- 1990-03-21
- type
- Contribution to journal
- publication status
- published
- in
- Journal of the National Cancer Institute
- volume
- 82
- issue
- 6
- pages
- 486 - 490
- publisher
- Oxford University Press
- external identifiers
-
- pmid:2313720
- scopus:0025236693
- ISSN
- 0027-8874
- DOI
- 10.1093/jnci/82.6.486
- language
- English
- LU publication?
- no
- id
- 02234877-3ee4-4572-9b9d-068470a3663c
- date added to LUP
- 2020-03-26 17:08:28
- date last changed
- 2024-02-16 14:15:12
@misc{02234877-3ee4-4572-9b9d-068470a3663c,
abstract = {{<p>In a case-control study including 237 cases with soft tissue sarcoma and 237 controls, previous jobs and exposures to different agents, including pesticides, were assessed. Exposure to phenoxyacetic acids or chlorophenols gave a statistically significant increased rate ratio (RR) of 1.80 [95% confidence interval (CI) = 1.02-3.18] for soft tissue sarcoma. Exposure to phenoxyacetic acids of all types gave a nonsignificantly increased RR of 1.34 (95% CI = 0.70-2.56). During the 1950s, exposure to 2,4,5-trichlorophenoxyacetic acid gave a threefold significantly increased risk. High-grade exposure to chlorophenols, which are also contaminated by dioxins, gave an RR of 5.25 (95% CI = 1.69-16.34). The increased risk was thus attributed to dioxin-contaminated phenoxy-acetic acids or chlorophenols that gave an RR of 2.43 (95% CI = 1.30-4.54). [J Natl Cancer Inst 82:486-490, 1990].</p>}},
author = {{Eriksson, Mikael and Hardell, Lennart and Adami, Hans Olov}},
issn = {{0027-8874}},
language = {{eng}},
month = {{03}},
number = {{6}},
pages = {{486--490}},
publisher = {{Oxford University Press}},
series = {{Journal of the National Cancer Institute}},
title = {{Exposure to dioxins as a risk factor for soft tissue sarcoma : A population - based case-control study}},
url = {{http://dx.doi.org/10.1093/jnci/82.6.486}},
doi = {{10.1093/jnci/82.6.486}},
volume = {{82}},
year = {{1990}},
}