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Early tibial subchondral bone texture changes after arthroscopic partial meniscectomy in knees without radiographic OA : A prospective cohort study

Wolski, Marcin ; Thorlund, Jonas B. ; Stachowiak, Gwidon W. ; Holsgaard-Larsen, Anders ; Creaby, Mark W. ; Jørgensen, Gitte M. ; Englund, Martin LU orcid and Podsiadlo, Pawel (2020) In Journal of Orthopaedic Research 38(8). p.1819-1825
Abstract

Arthroscopic partial meniscectomy (APM) may lead to changes in underlying trabecular bone (TB) structure potentially promoting the development of knee joint osteoarthritis. Our aim was to investigate if there are early changes occurring in tibial subchondral TB texture in the leg undergoing medial APM compared with the unoperated non-injured contra-lateral leg. The bone texture was measured as the medial-to-lateral ratio of fractal dimensions (FD) calculated for regions selected on weight-bearing anteroposterior tibiofemoral x-rays. Twenty-one subjects before and 12 months after APM were included from 374 patients scheduled for unilateral medial APM. The medial-to-lateral ratio was calculated for horizontal, vertical, and roughest FDs... (More)

Arthroscopic partial meniscectomy (APM) may lead to changes in underlying trabecular bone (TB) structure potentially promoting the development of knee joint osteoarthritis. Our aim was to investigate if there are early changes occurring in tibial subchondral TB texture in the leg undergoing medial APM compared with the unoperated non-injured contra-lateral leg. The bone texture was measured as the medial-to-lateral ratio of fractal dimensions (FD) calculated for regions selected on weight-bearing anteroposterior tibiofemoral x-rays. Twenty-one subjects before and 12 months after APM were included from 374 patients scheduled for unilateral medial APM. The medial-to-lateral ratio was calculated for horizontal, vertical, and roughest FDs respectively. Higher FD means higher bone roughness. Each FD was calculated over a range of scales using a variance orientation transform method. Mean values of medial-to-lateral horizontal FD calculated for APM knees at follow-up were higher than those at baseline. For unoperated knees the values were lower. The difference in the horizontal FD change from baseline to follow-up between APM and contra-lateral legs was 0.028 (95% CI, 0.004-0.052). The bone roughness changes may reflect the increase in peak knee adduction moment (KAM) and KAM impulse during walking reported for the same cohort in a previous study. They may also reflect early signs of osteoarthritis development and thus, we speculate that individuals with increased bone texture roughness ratio after APM might be at higher risk of knee osteoarthritis development.

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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
fractal analysis, meniscectomy, osteoarthritis, tibiofemoral
in
Journal of Orthopaedic Research
volume
38
issue
8
pages
7 pages
publisher
John Wiley & Sons Inc.
external identifiers
  • scopus:85078679199
  • pmid:31965586
ISSN
0736-0266
DOI
10.1002/jor.24593
language
English
LU publication?
yes
id
025c09f9-ad87-41eb-97b6-09741ff9ad92
date added to LUP
2020-02-17 10:58:28
date last changed
2024-04-03 02:31:09
@article{025c09f9-ad87-41eb-97b6-09741ff9ad92,
  abstract     = {{<p>Arthroscopic partial meniscectomy (APM) may lead to changes in underlying trabecular bone (TB) structure potentially promoting the development of knee joint osteoarthritis. Our aim was to investigate if there are early changes occurring in tibial subchondral TB texture in the leg undergoing medial APM compared with the unoperated non-injured contra-lateral leg. The bone texture was measured as the medial-to-lateral ratio of fractal dimensions (FD) calculated for regions selected on weight-bearing anteroposterior tibiofemoral x-rays. Twenty-one subjects before and 12 months after APM were included from 374 patients scheduled for unilateral medial APM. The medial-to-lateral ratio was calculated for horizontal, vertical, and roughest FDs respectively. Higher FD means higher bone roughness. Each FD was calculated over a range of scales using a variance orientation transform method. Mean values of medial-to-lateral horizontal FD calculated for APM knees at follow-up were higher than those at baseline. For unoperated knees the values were lower. The difference in the horizontal FD change from baseline to follow-up between APM and contra-lateral legs was 0.028 (95% CI, 0.004-0.052). The bone roughness changes may reflect the increase in peak knee adduction moment (KAM) and KAM impulse during walking reported for the same cohort in a previous study. They may also reflect early signs of osteoarthritis development and thus, we speculate that individuals with increased bone texture roughness ratio after APM might be at higher risk of knee osteoarthritis development.</p>}},
  author       = {{Wolski, Marcin and Thorlund, Jonas B. and Stachowiak, Gwidon W. and Holsgaard-Larsen, Anders and Creaby, Mark W. and Jørgensen, Gitte M. and Englund, Martin and Podsiadlo, Pawel}},
  issn         = {{0736-0266}},
  keywords     = {{fractal analysis; meniscectomy; osteoarthritis; tibiofemoral}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{1819--1825}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Journal of Orthopaedic Research}},
  title        = {{Early tibial subchondral bone texture changes after arthroscopic partial meniscectomy in knees without radiographic OA : A prospective cohort study}},
  url          = {{http://dx.doi.org/10.1002/jor.24593}},
  doi          = {{10.1002/jor.24593}},
  volume       = {{38}},
  year         = {{2020}},
}