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The value of C-reactive protein (CRP) determinations in patients with suspected acute appendicitis.

Mikaelsson, C. and Arnbjörnsson, E. LU (1984) In Annales Chirurgiae et Gynaecologiae 73(5). p.281-284
Abstract

The clinical usefulness of the preoperative determination of C-Reactive protein (CRP) in patients with suspected acute appendicitis was studied in 156 consecutive patients undergoing acute appendicectomy. The CRP values were found to increase with an advancing stage of the appendiceal inflammation found at operation and the length of the preoperative phase of illness. Eight out of 66 patients with a phlegmonous appendix found at operation showed no signs of bacterial infection, as revealed by an increased C-Reactive protein level. These results suggest that a preoperative quantitative determination of the C-Reactive protein in patients with suspected acute appendicitis might add a valuable parameter to the laboratory profile in this... (More)

The clinical usefulness of the preoperative determination of C-Reactive protein (CRP) in patients with suspected acute appendicitis was studied in 156 consecutive patients undergoing acute appendicectomy. The CRP values were found to increase with an advancing stage of the appendiceal inflammation found at operation and the length of the preoperative phase of illness. Eight out of 66 patients with a phlegmonous appendix found at operation showed no signs of bacterial infection, as revealed by an increased C-Reactive protein level. These results suggest that a preoperative quantitative determination of the C-Reactive protein in patients with suspected acute appendicitis might add a valuable parameter to the laboratory profile in this condition and can be used for the selection of those patients who would benefit from a preoperatively administered antibiotic prophylaxis. Furthermore, these results might support the theory that an obstruction of the appendix lumen is the most important factor in the genesis of acute appendicitis.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Annales Chirurgiae et Gynaecologiae
volume
73
issue
5
pages
281 - 284
publisher
Finnish Surgical Society
external identifiers
  • scopus:0021697091
ISSN
0355-9521
language
English
LU publication?
yes
id
032359c3-f218-42ab-9589-ea375797ab51
date added to LUP
2018-11-09 09:34:43
date last changed
2019-01-20 05:59:51
@article{032359c3-f218-42ab-9589-ea375797ab51,
  abstract     = {<p>The clinical usefulness of the preoperative determination of C-Reactive protein (CRP) in patients with suspected acute appendicitis was studied in 156 consecutive patients undergoing acute appendicectomy. The CRP values were found to increase with an advancing stage of the appendiceal inflammation found at operation and the length of the preoperative phase of illness. Eight out of 66 patients with a phlegmonous appendix found at operation showed no signs of bacterial infection, as revealed by an increased C-Reactive protein level. These results suggest that a preoperative quantitative determination of the C-Reactive protein in patients with suspected acute appendicitis might add a valuable parameter to the laboratory profile in this condition and can be used for the selection of those patients who would benefit from a preoperatively administered antibiotic prophylaxis. Furthermore, these results might support the theory that an obstruction of the appendix lumen is the most important factor in the genesis of acute appendicitis.</p>},
  author       = {Mikaelsson, C. and Arnbjörnsson, E.},
  issn         = {0355-9521},
  language     = {eng},
  month        = {12},
  number       = {5},
  pages        = {281--284},
  publisher    = {Finnish Surgical Society},
  series       = {Annales Chirurgiae et Gynaecologiae},
  title        = {The value of C-reactive protein (CRP) determinations in patients with suspected acute appendicitis.},
  volume       = {73},
  year         = {1984},
}