DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.
Hall, Elin LU ; Dayeh, Tasnim LU ; Kirkpatrick, Clare L ; Wollheim, Claes LU ; Dekker Nitert, Marloes LU and Ling, Charlotte LU
(2013)
In BMC Medical Genetics
14(Jul,23).
- Abstract
- Insulin secretion is enhanced upon the binding of Glucagon-like peptide-1 (GLP-1) to its receptor (GLP1R) in pancreatic β cells. Although a reduced expression of GLP1R in pancreatic islets from type 2 diabetic patients and hyperglycaemic rats has been established, it is still unknown if this is caused by differential DNA methylation of GLP1R in pancreatic islets of type 2 diabetic patients.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3955639
- author
- Hall, Elin
LU
; Dayeh, Tasnim
LU
; Kirkpatrick, Clare L
; Wollheim, Claes
LU
; Dekker Nitert, Marloes
LU
and Ling, Charlotte
LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Medical Genetics
- volume
- 14
- issue
- Jul,23
- article number
- 76
- publisher
- BioMed Central (BMC)
- external identifiers
-
- wos:000322381800001
- pmid:23879380
- scopus:84880335165
- pmid:23879380
- ISSN
- 1471-2350
- DOI
- 10.1186/1471-2350-14-76
- language
- English
- LU publication?
- yes
- id
- 0484c8c4-2599-42fe-a591-f2bb0edf629e (old id 3955639)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23879380?dopt=Abstract
- date added to LUP
- 2016-04-01 13:41:07
- date last changed
- 2024-04-10 08:56:50
@article{0484c8c4-2599-42fe-a591-f2bb0edf629e,
abstract = {{Insulin secretion is enhanced upon the binding of Glucagon-like peptide-1 (GLP-1) to its receptor (GLP1R) in pancreatic β cells. Although a reduced expression of GLP1R in pancreatic islets from type 2 diabetic patients and hyperglycaemic rats has been established, it is still unknown if this is caused by differential DNA methylation of GLP1R in pancreatic islets of type 2 diabetic patients.}},
author = {{Hall, Elin and Dayeh, Tasnim and Kirkpatrick, Clare L and Wollheim, Claes and Dekker Nitert, Marloes and Ling, Charlotte}},
issn = {{1471-2350}},
language = {{eng}},
number = {{Jul,23}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Medical Genetics}},
title = {{DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.}},
url = {{https://lup.lub.lu.se/search/files/3531610/4146435}},
doi = {{10.1186/1471-2350-14-76}},
volume = {{14}},
year = {{2013}},
}