Detection and possible functional influence of antibodies directed againt the pancreatic islet cell surface.
Lernmark, A. LU
; Kanatsuna, T.
; Rubenstein, A. H.
and Steiner, D. F.
(1979)
In Advances in Experimental Medicine and Biology
119.
p.157-163
- Abstract
Antibodies directed towards determinants on the surface of rat islet cells can be detected qualitatively by the indirect immunofluorescence or quantitatively by a specific radioassay for IgG. Antibodies are found in insulin-dependent diabetics or in rabbits immunized with islet cells. Such antibodies may affect the B-cell function as indicated by the inhibition of incorporation of radioactive leucine into proinsulin/insulin in vitro.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/053f8ac2-ada6-4655-9b98-fef0106e542e
- author
- Lernmark, A.
LU
; Kanatsuna, T.
; Rubenstein, A. H.
and Steiner, D. F.
- publishing date
- 1979-01-01
- type
- Contribution to journal
- publication status
- published
- in
- Advances in Experimental Medicine and Biology
- volume
- 119
- pages
- 7 pages
- publisher
- Springer
- external identifiers
-
- pmid:91312
- scopus:0018337782
- ISSN
- 0065-2598
- DOI
- 10.1007/978-1-4615-9110-8_23
- language
- English
- LU publication?
- no
- id
- 053f8ac2-ada6-4655-9b98-fef0106e542e
- date added to LUP
- 2019-09-18 12:07:37
- date last changed
- 2024-03-13 08:15:21
@article{053f8ac2-ada6-4655-9b98-fef0106e542e,
abstract = {{<p>Antibodies directed towards determinants on the surface of rat islet cells can be detected qualitatively by the indirect immunofluorescence or quantitatively by a specific radioassay for IgG. Antibodies are found in insulin-dependent diabetics or in rabbits immunized with islet cells. Such antibodies may affect the B-cell function as indicated by the inhibition of incorporation of radioactive leucine into proinsulin/insulin in vitro.</p>}},
author = {{Lernmark, A. and Kanatsuna, T. and Rubenstein, A. H. and Steiner, D. F.}},
issn = {{0065-2598}},
language = {{eng}},
month = {{01}},
pages = {{157--163}},
publisher = {{Springer}},
series = {{Advances in Experimental Medicine and Biology}},
title = {{Detection and possible functional influence of antibodies directed againt the pancreatic islet cell surface.}},
url = {{http://dx.doi.org/10.1007/978-1-4615-9110-8_23}},
doi = {{10.1007/978-1-4615-9110-8_23}},
volume = {{119}},
year = {{1979}},
}