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Chronic lymphocytic leukaemia and multiple myeloma

Pulenzas, N. ; Porwit, A. LU ; Craddock, K. J. ; Thavarajah, N. ; Lechner, B. ; Holden, L. ; Lauzon, N. and Chow, Edward (2014) In Hong Kong Journal of Radiology 17(2). p.135-139
Abstract

Association of chronic lymphocytic leukaemia and multiple myeloma in the same individual is rare. These malignancies may be related through a common clonal origin, or exist as separate malignancies from different clones. Multiple myeloma may exist simultaneously with chronic lymphocytic leukaemia, or be diagnosed several months after chronic lymphocytic leukaemia. Common symptoms experienced in these rare cases are generally a combination of clinical features typically seen in chronic lymphocytic leukaemia and multiple myeloma separately. This report describes a 76-year-old man with coexisting chronic lymphocytic leukaemia and multiple myeloma. Diagnosis of chronic lymphocytic leukaemia preceded the diagnosis of multiple myeloma by... (More)

Association of chronic lymphocytic leukaemia and multiple myeloma in the same individual is rare. These malignancies may be related through a common clonal origin, or exist as separate malignancies from different clones. Multiple myeloma may exist simultaneously with chronic lymphocytic leukaemia, or be diagnosed several months after chronic lymphocytic leukaemia. Common symptoms experienced in these rare cases are generally a combination of clinical features typically seen in chronic lymphocytic leukaemia and multiple myeloma separately. This report describes a 76-year-old man with coexisting chronic lymphocytic leukaemia and multiple myeloma. Diagnosis of chronic lymphocytic leukaemia preceded the diagnosis of multiple myeloma by approximately 4 years, and multiple myeloma presented with translocation t(11;14) that was not found in chronic lymphocytic leukaemia cells.

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author
; ; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bone marrow, Chromosome aberrations, Leukemia, lymphocytic, chronic, B-cell, Multiple myeloma
in
Hong Kong Journal of Radiology
volume
17
issue
2
pages
5 pages
publisher
Hong Kong Academy of Medicine Press
external identifiers
  • scopus:84903161742
ISSN
2223-6619
DOI
10.12809/hkjr1313177
language
English
LU publication?
no
id
0578c845-2f05-4d40-a4d3-6f57204b59d7
date added to LUP
2019-05-22 09:50:36
date last changed
2022-01-31 20:38:01
@article{0578c845-2f05-4d40-a4d3-6f57204b59d7,
  abstract     = {{<p>Association of chronic lymphocytic leukaemia and multiple myeloma in the same individual is rare. These malignancies may be related through a common clonal origin, or exist as separate malignancies from different clones. Multiple myeloma may exist simultaneously with chronic lymphocytic leukaemia, or be diagnosed several months after chronic lymphocytic leukaemia. Common symptoms experienced in these rare cases are generally a combination of clinical features typically seen in chronic lymphocytic leukaemia and multiple myeloma separately. This report describes a 76-year-old man with coexisting chronic lymphocytic leukaemia and multiple myeloma. Diagnosis of chronic lymphocytic leukaemia preceded the diagnosis of multiple myeloma by approximately 4 years, and multiple myeloma presented with translocation t(11;14) that was not found in chronic lymphocytic leukaemia cells.</p>}},
  author       = {{Pulenzas, N. and Porwit, A. and Craddock, K. J. and Thavarajah, N. and Lechner, B. and Holden, L. and Lauzon, N. and Chow, Edward}},
  issn         = {{2223-6619}},
  keywords     = {{Bone marrow; Chromosome aberrations; Leukemia, lymphocytic, chronic, B-cell; Multiple myeloma}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{2}},
  pages        = {{135--139}},
  publisher    = {{Hong Kong Academy of Medicine Press}},
  series       = {{Hong Kong Journal of Radiology}},
  title        = {{Chronic lymphocytic leukaemia and multiple myeloma}},
  url          = {{http://dx.doi.org/10.12809/hkjr1313177}},
  doi          = {{10.12809/hkjr1313177}},
  volume       = {{17}},
  year         = {{2014}},
}