Body mass index and progressive hand osteoarthritis : data from the Oslo hand osteoarthritis cohort
(2015) In Scandinavian Journal of Rheumatology 44(4). p.6-331- Abstract
OBJECTIVES: Few longitudinal studies have studied the association between body mass index (BMI) and hand osteoarthritis (OA). We aimed to explore the association between BMI and progressive hand OA in a longitudinal study of the Oslo hand OA cohort.
METHOD: Participants with existing hand OA had hand radiographs and BMI data taken at baseline and 7-year follow-up (n = 103). The radiographs were read according to the Kellgren-Lawrence (KL) scale. First, we examined the association between baseline BMI and incident OA (KL grade ≥ 2) in joints without OA at baseline (adjusted for age and sex) using generalized estimating equation (GEE) analyses. Second, we examined whether changes in BMI from baseline to follow-up were associated... (More)
OBJECTIVES: Few longitudinal studies have studied the association between body mass index (BMI) and hand osteoarthritis (OA). We aimed to explore the association between BMI and progressive hand OA in a longitudinal study of the Oslo hand OA cohort.
METHOD: Participants with existing hand OA had hand radiographs and BMI data taken at baseline and 7-year follow-up (n = 103). The radiographs were read according to the Kellgren-Lawrence (KL) scale. First, we examined the association between baseline BMI and incident OA (KL grade ≥ 2) in joints without OA at baseline (adjusted for age and sex) using generalized estimating equation (GEE) analyses. Second, we examined whether changes in BMI from baseline to follow-up were associated with increasing KL sum score from baseline to follow-up using linear regression. We repeated the analyses using changes in number of joints with symptomatic OA and patient-reported pain and physical function as the outcome.
RESULTS: The mean (SD) age at baseline was 61.6 (5.6) years and 91 (94%) of the cohort were women. The mean (SD) BMI was 25.7 (4.0) kg/m(2) at baseline and the mean (SD) BMI change was 1.1 (2.0) kg/m(2). There was no relationship between baseline BMI and development of more joints with OA during follow-up. Similarly, there was no association between change in BMI and hand OA progression, increasing hand pain or disability.
CONCLUSIONS: In the Oslo hand OA cohort, higher BMI was not related to hand OA progression.
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- author
- Magnusson, K LU ; Slatkowsky-Christensen, B ; van der Heijde, D ; Kvien, T K ; Hagen, K B and Haugen, I K
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Aged, Arthralgia/epidemiology, Body Mass Index, Cohort Studies, Disability Evaluation, Disease Progression, Female, Follow-Up Studies, Hand Joints, Humans, Incidence, Linear Models, Longitudinal Studies, Male, Middle Aged, Norway/epidemiology, Obesity/complications, Osteoarthritis/epidemiology, Risk Factors
- in
- Scandinavian Journal of Rheumatology
- volume
- 44
- issue
- 4
- pages
- 6 pages
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:25742965
- scopus:84937785712
- ISSN
- 1502-7732
- DOI
- 10.3109/03009742.2014.994560
- language
- English
- LU publication?
- no
- id
- 0610d58e-d97b-4201-aed9-e138004105b4
- date added to LUP
- 2018-11-29 15:11:54
- date last changed
- 2024-01-15 08:14:45
@article{0610d58e-d97b-4201-aed9-e138004105b4,
abstract = {{<p>OBJECTIVES: Few longitudinal studies have studied the association between body mass index (BMI) and hand osteoarthritis (OA). We aimed to explore the association between BMI and progressive hand OA in a longitudinal study of the Oslo hand OA cohort.</p><p>METHOD: Participants with existing hand OA had hand radiographs and BMI data taken at baseline and 7-year follow-up (n = 103). The radiographs were read according to the Kellgren-Lawrence (KL) scale. First, we examined the association between baseline BMI and incident OA (KL grade ≥ 2) in joints without OA at baseline (adjusted for age and sex) using generalized estimating equation (GEE) analyses. Second, we examined whether changes in BMI from baseline to follow-up were associated with increasing KL sum score from baseline to follow-up using linear regression. We repeated the analyses using changes in number of joints with symptomatic OA and patient-reported pain and physical function as the outcome.</p><p>RESULTS: The mean (SD) age at baseline was 61.6 (5.6) years and 91 (94%) of the cohort were women. The mean (SD) BMI was 25.7 (4.0) kg/m(2) at baseline and the mean (SD) BMI change was 1.1 (2.0) kg/m(2). There was no relationship between baseline BMI and development of more joints with OA during follow-up. Similarly, there was no association between change in BMI and hand OA progression, increasing hand pain or disability.</p><p>CONCLUSIONS: In the Oslo hand OA cohort, higher BMI was not related to hand OA progression.</p>}},
author = {{Magnusson, K and Slatkowsky-Christensen, B and van der Heijde, D and Kvien, T K and Hagen, K B and Haugen, I K}},
issn = {{1502-7732}},
keywords = {{Aged; Arthralgia/epidemiology; Body Mass Index; Cohort Studies; Disability Evaluation; Disease Progression; Female; Follow-Up Studies; Hand Joints; Humans; Incidence; Linear Models; Longitudinal Studies; Male; Middle Aged; Norway/epidemiology; Obesity/complications; Osteoarthritis/epidemiology; Risk Factors}},
language = {{eng}},
number = {{4}},
pages = {{6--331}},
publisher = {{Taylor & Francis}},
series = {{Scandinavian Journal of Rheumatology}},
title = {{Body mass index and progressive hand osteoarthritis : data from the Oslo hand osteoarthritis cohort}},
url = {{http://dx.doi.org/10.3109/03009742.2014.994560}},
doi = {{10.3109/03009742.2014.994560}},
volume = {{44}},
year = {{2015}},
}