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Non-invasive multimodal imaging of diabetic retinopathy : A survey on treatment methods and nanotheranostics

Sadasivam, Rajkumar ; Packirisamy, Gopinath ; Shakya, Snehlata LU and Goswami, Mayank (2021) In Nanotheranostics 5(2). p.166-181
Abstract

Diabetes Retinopathy (DR) is one of the most prominent microvascular complications of diabetes. It is one of the pre-eminent causes for vision impairment followed by blindness among the working-age population worldwide. The de facto cause for DR remains challenging, despite several efforts made to unveil the mechanism underlying the pathology of DR. There is quite less availability of the low cost pre-emptive theranostic imaging tools in terms of in-depth resolution, due to the multiple factors involved in the etiology of DR. This review work comprehensively explores the various reports and research works on all perspectives of diabetic retinopathy (DR), and its mechanism. It also discusses various advanced non-destructive imaging... (More)

Diabetes Retinopathy (DR) is one of the most prominent microvascular complications of diabetes. It is one of the pre-eminent causes for vision impairment followed by blindness among the working-age population worldwide. The de facto cause for DR remains challenging, despite several efforts made to unveil the mechanism underlying the pathology of DR. There is quite less availability of the low cost pre-emptive theranostic imaging tools in terms of in-depth resolution, due to the multiple factors involved in the etiology of DR. This review work comprehensively explores the various reports and research works on all perspectives of diabetic retinopathy (DR), and its mechanism. It also discusses various advanced non-destructive imaging modalities, current, and future treatment approaches. Further, the application of various nanoparticle-based drug delivery strategies used for the treatment of DR are also discussed. In a nutshell, the present review work bolsters the pursuit of the development of an advanced non-invasive optical imaging modal with a nano-theranostic approach for the future diagnosis and treatment of DR and its associated ocular complications.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Diabetic retinopathy, Drugs and nano-theranostics, Imaging biomarkers, Treatment
in
Nanotheranostics
volume
5
issue
2
pages
16 pages
publisher
Ivyspring International Publisher
external identifiers
  • pmid:33564616
  • scopus:85101260932
ISSN
2206-7418
DOI
10.7150/ntno.56015
language
English
LU publication?
yes
id
062eee99-71a4-420c-9d97-1da9ac68858f
date added to LUP
2021-03-11 09:48:17
date last changed
2024-06-13 08:23:52
@article{062eee99-71a4-420c-9d97-1da9ac68858f,
  abstract     = {{<p>Diabetes Retinopathy (DR) is one of the most prominent microvascular complications of diabetes. It is one of the pre-eminent causes for vision impairment followed by blindness among the working-age population worldwide. The de facto cause for DR remains challenging, despite several efforts made to unveil the mechanism underlying the pathology of DR. There is quite less availability of the low cost pre-emptive theranostic imaging tools in terms of in-depth resolution, due to the multiple factors involved in the etiology of DR. This review work comprehensively explores the various reports and research works on all perspectives of diabetic retinopathy (DR), and its mechanism. It also discusses various advanced non-destructive imaging modalities, current, and future treatment approaches. Further, the application of various nanoparticle-based drug delivery strategies used for the treatment of DR are also discussed. In a nutshell, the present review work bolsters the pursuit of the development of an advanced non-invasive optical imaging modal with a nano-theranostic approach for the future diagnosis and treatment of DR and its associated ocular complications.</p>}},
  author       = {{Sadasivam, Rajkumar and Packirisamy, Gopinath and Shakya, Snehlata and Goswami, Mayank}},
  issn         = {{2206-7418}},
  keywords     = {{Diabetic retinopathy; Drugs and nano-theranostics; Imaging biomarkers; Treatment}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{166--181}},
  publisher    = {{Ivyspring International Publisher}},
  series       = {{Nanotheranostics}},
  title        = {{Non-invasive multimodal imaging of diabetic retinopathy : A survey on treatment methods and nanotheranostics}},
  url          = {{http://dx.doi.org/10.7150/ntno.56015}},
  doi          = {{10.7150/ntno.56015}},
  volume       = {{5}},
  year         = {{2021}},
}