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Clinical characteristics at hospital discharge that predict cardiovascular readmission within 100 days in heart failure patients – An observational study

Davidge, Jason LU ; Halling, Anders LU ; Ashfaq, Awais ; Etminani, Kobra and Agvall, Björn (2023) In International Journal of Cardiology: Cardiovascular Risk and Prevention 16.
Abstract

Background: After a heart failure (HF) hospital discharge, the risk of a cardiovascular (CV) related event is highest in the following 100 days. It is important to identify factors associated with increased risk of readmission. Method: This retrospective, population-based study examined HF patients in Region Halland (RH), Sweden, hospitalized with a HF diagnosis between 2017 and 2019. Data regarding patient clinical characteristics were retrieved from the Regional healthcare Information Platform from admission until 100 days post-discharge. Primary outcome was readmission due to a CV related event within 100 days. Results: There were 5029 included patients being admitted for HF and discharged and 1966 (39%) were newly diagnosed.... (More)

Background: After a heart failure (HF) hospital discharge, the risk of a cardiovascular (CV) related event is highest in the following 100 days. It is important to identify factors associated with increased risk of readmission. Method: This retrospective, population-based study examined HF patients in Region Halland (RH), Sweden, hospitalized with a HF diagnosis between 2017 and 2019. Data regarding patient clinical characteristics were retrieved from the Regional healthcare Information Platform from admission until 100 days post-discharge. Primary outcome was readmission due to a CV related event within 100 days. Results: There were 5029 included patients being admitted for HF and discharged and 1966 (39%) were newly diagnosed. Echocardiography was available for 3034 (60%) patients and 1644 (33%) had their first echocardiography while admitted. The distribution of HF-phenotypes was 33% HF with reduced ejection fraction (EF), 29% HF with mildly reduced EF and 38% HF with preserved EF. Within 100 days, 1586 (33%) patients were readmitted, and 614 (12%) died. A Cox regression model showed that advanced age, longer hospital length of stay, renal impairment, high heart rate and elevated NT-proBNP were associated with an increased risk of readmission regardless of HF-phenotype. Women and increased blood pressure are associated with a reduced risk of readmission. Conclusions: One third had a CV-readmission within 100 days. This study found clinical factors already present at discharge that are associated with increased risk of readmission which should be considered at discharge.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Heart failure, Hospital readmission, Risk factors
in
International Journal of Cardiology: Cardiovascular Risk and Prevention
volume
16
article number
200176
publisher
Elsevier
external identifiers
  • scopus:85148749401
  • pmid:36865412
ISSN
2772-4875
DOI
10.1016/j.ijcrp.2023.200176
language
English
LU publication?
yes
id
0754a4c3-469a-4d6d-ba5c-38a4eeb85bb3
date added to LUP
2023-03-15 11:05:23
date last changed
2024-09-18 17:34:44
@article{0754a4c3-469a-4d6d-ba5c-38a4eeb85bb3,
  abstract     = {{<p>Background: After a heart failure (HF) hospital discharge, the risk of a cardiovascular (CV) related event is highest in the following 100 days. It is important to identify factors associated with increased risk of readmission. Method: This retrospective, population-based study examined HF patients in Region Halland (RH), Sweden, hospitalized with a HF diagnosis between 2017 and 2019. Data regarding patient clinical characteristics were retrieved from the Regional healthcare Information Platform from admission until 100 days post-discharge. Primary outcome was readmission due to a CV related event within 100 days. Results: There were 5029 included patients being admitted for HF and discharged and 1966 (39%) were newly diagnosed. Echocardiography was available for 3034 (60%) patients and 1644 (33%) had their first echocardiography while admitted. The distribution of HF-phenotypes was 33% HF with reduced ejection fraction (EF), 29% HF with mildly reduced EF and 38% HF with preserved EF. Within 100 days, 1586 (33%) patients were readmitted, and 614 (12%) died. A Cox regression model showed that advanced age, longer hospital length of stay, renal impairment, high heart rate and elevated NT-proBNP were associated with an increased risk of readmission regardless of HF-phenotype. Women and increased blood pressure are associated with a reduced risk of readmission. Conclusions: One third had a CV-readmission within 100 days. This study found clinical factors already present at discharge that are associated with increased risk of readmission which should be considered at discharge.</p>}},
  author       = {{Davidge, Jason and Halling, Anders and Ashfaq, Awais and Etminani, Kobra and Agvall, Björn}},
  issn         = {{2772-4875}},
  keywords     = {{Heart failure; Hospital readmission; Risk factors}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{International Journal of Cardiology: Cardiovascular Risk and Prevention}},
  title        = {{Clinical characteristics at hospital discharge that predict cardiovascular readmission within 100 days in heart failure patients – An observational study}},
  url          = {{http://dx.doi.org/10.1016/j.ijcrp.2023.200176}},
  doi          = {{10.1016/j.ijcrp.2023.200176}},
  volume       = {{16}},
  year         = {{2023}},
}