Postpartum thromboembolism: severe events might be preventable using a new risk score model.
(2008) In Vascular Health and Risk Management 4(5). p.1081-1087- Abstract
- BACKGROUND: Pregnancy-related venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality. A new risk assessment model for VTE in relation to pregnancy has been introduced in Sweden. We wished to determine the proportion of preventable VTE cases if the model had been in use and make a brief cost-benefit analysis. METHODS: A hospital-based retrospective case-control study of all postpartum thromboembolic instances of deep venous thrombosis and pulmonary embolisms during a 16-year period. Large anamnestic risk factors at the time of delivery were assessed. We correlated the findings with the new Swedish guidelines for thromboprophylaxis. RESULTS: We found 37 cases of postpartum VTE during the study period. Nineteen of... (More)
- BACKGROUND: Pregnancy-related venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality. A new risk assessment model for VTE in relation to pregnancy has been introduced in Sweden. We wished to determine the proportion of preventable VTE cases if the model had been in use and make a brief cost-benefit analysis. METHODS: A hospital-based retrospective case-control study of all postpartum thromboembolic instances of deep venous thrombosis and pulmonary embolisms during a 16-year period. Large anamnestic risk factors at the time of delivery were assessed. We correlated the findings with the new Swedish guidelines for thromboprophylaxis. RESULTS: We found 37 cases of postpartum VTE during the study period. Nineteen of all VTE cases (51%) and eight out of eleven of cases of pulmonary embolism (73%) had two or more large anamnestic risk factors, ie, they would have been subjected to thromboprophylaxis if the new guidelines had been used. The cost of each preventable VTE was lower than treating a VTE. CONCLUSION: Approximately one-half of postpartum VTE cases and 70% of pulmonary emboli cases have at least two large risk factors and might be preventable using the new algorithm. From the perspective of the health care system the new recommendations appears to be cost-effective. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1302999
- author
- Lindqvist, Pelle LU ; Torsson, Jelena LU ; Almqvist, Asa and Björgell, Ola LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Fibrinolytic Agents: economics, Puerperal Disorders: economics, Fibrinolytic Agents: therapeutic use, Puerperal Disorders: etiology, Puerperal Disorders: prevention & control, Pulmonary Embolism: etiology, Pulmonary Embolism: economics, Thromboembolism: etiology, Thromboembolism: economics, Pulmonary Embolism: prevention & control, Venous Thrombosis: etiology, Thromboembolism: prevention & control, Venous Thrombosis: economics, Venous Thrombosis: prevention & control
- in
- Vascular Health and Risk Management
- volume
- 4
- issue
- 5
- pages
- 1081 - 1087
- publisher
- Dove Medical Press Ltd.
- external identifiers
-
- pmid:19183756
- scopus:56849111156
- ISSN
- 1178-2048
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Medical Radiology Unit (013241410)
- id
- 0777dedc-6b1e-4b7a-952e-e8f197172967 (old id 1302999)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19183756?dopt=Abstract
- date added to LUP
- 2016-04-04 08:33:01
- date last changed
- 2022-01-29 03:32:15
@article{0777dedc-6b1e-4b7a-952e-e8f197172967,
abstract = {{BACKGROUND: Pregnancy-related venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality. A new risk assessment model for VTE in relation to pregnancy has been introduced in Sweden. We wished to determine the proportion of preventable VTE cases if the model had been in use and make a brief cost-benefit analysis. METHODS: A hospital-based retrospective case-control study of all postpartum thromboembolic instances of deep venous thrombosis and pulmonary embolisms during a 16-year period. Large anamnestic risk factors at the time of delivery were assessed. We correlated the findings with the new Swedish guidelines for thromboprophylaxis. RESULTS: We found 37 cases of postpartum VTE during the study period. Nineteen of all VTE cases (51%) and eight out of eleven of cases of pulmonary embolism (73%) had two or more large anamnestic risk factors, ie, they would have been subjected to thromboprophylaxis if the new guidelines had been used. The cost of each preventable VTE was lower than treating a VTE. CONCLUSION: Approximately one-half of postpartum VTE cases and 70% of pulmonary emboli cases have at least two large risk factors and might be preventable using the new algorithm. From the perspective of the health care system the new recommendations appears to be cost-effective.}},
author = {{Lindqvist, Pelle and Torsson, Jelena and Almqvist, Asa and Björgell, Ola}},
issn = {{1178-2048}},
keywords = {{Fibrinolytic Agents: economics; Puerperal Disorders: economics; Fibrinolytic Agents: therapeutic use; Puerperal Disorders: etiology; Puerperal Disorders: prevention & control; Pulmonary Embolism: etiology; Pulmonary Embolism: economics; Thromboembolism: etiology; Thromboembolism: economics; Pulmonary Embolism: prevention & control; Venous Thrombosis: etiology; Thromboembolism: prevention & control; Venous Thrombosis: economics; Venous Thrombosis: prevention & control}},
language = {{eng}},
number = {{5}},
pages = {{1081--1087}},
publisher = {{Dove Medical Press Ltd.}},
series = {{Vascular Health and Risk Management}},
title = {{Postpartum thromboembolism: severe events might be preventable using a new risk score model.}},
url = {{http://www.ncbi.nlm.nih.gov/pubmed/19183756?dopt=Abstract}},
volume = {{4}},
year = {{2008}},
}