The role of breast tomosynthesis in a predominantly dense breast population at a tertiary breast centre : breast density assessment and diagnostic performance in comparison with MRI
(2018) In European Radiology 28(8). p.3194-3203- Abstract
Objectives: To compare breast density measured on digital breast tomosynthesis (DBT) (BI-RADS-based breast composition and fully-automatic estimation) and magnetic resonance imaging (MRI) (BI-RADS amount of fibroglandular tissue), and to evaluate the diagnostic performance in terms of sensitivity and specificity of DBT and MRI in a predominantly dense breast population. Methods: Between 2015 and 2016, 152 women with 103 breast malignancies, who underwent 3-T breast MRI and DBT within 2 months’ time, were enrolled in this study. Breast composition/fibroglandular tissue and findings on DBT (two readers) and MRI were reported using BI-RADS 5th edition. Digital mammography images were analysed for breast percent density (PD) using the Libra... (More)
Objectives: To compare breast density measured on digital breast tomosynthesis (DBT) (BI-RADS-based breast composition and fully-automatic estimation) and magnetic resonance imaging (MRI) (BI-RADS amount of fibroglandular tissue), and to evaluate the diagnostic performance in terms of sensitivity and specificity of DBT and MRI in a predominantly dense breast population. Methods: Between 2015 and 2016, 152 women with 103 breast malignancies, who underwent 3-T breast MRI and DBT within 2 months’ time, were enrolled in this study. Breast composition/fibroglandular tissue and findings on DBT (two readers) and MRI were reported using BI-RADS 5th edition. Digital mammography images were analysed for breast percent density (PD) using the Libra software tool. Results: A majority of women had dense breasts as categorised by breast composition c (heterogeneously dense) (68%) and d (extremely dense) (15%). The mean PD was 44% (range, 18-89%) and the correlation between breast composition and PD was r = 0.6. The diagnostic performance of MRI was significantly higher compared to DBT for one reader as described by the area under the receiver operating characteristic (ROC) curve (p = 0.004) and of borderline significance for the other reader (p = 0.052). Conclusions: MRI had higher diagnostic performance than DBT in a dense breast population in the tertiary setting. Key Points: • MRI had higher diagnostic performance than DBT in a dense breast population• Diagnostic performance of DBT was comparable to MRI in women with fatty breasts• MRI was superior to DBT in preoperative breast cancer size assessment
(Less)
- author
- Förnvik, Daniel LU ; Kataoka, Masako ; Iima, Mami ; Ohashi, Akane ; Kanao, Shotaro ; Toi, Masakazu and Togashi, Kaori
- organization
- publishing date
- 2018-08
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Breast cancer, Breast density, Diagnostic techniques and procedures, Digital breast tomosynthesis, Magnetic resonance imaging
- in
- European Radiology
- volume
- 28
- issue
- 8
- pages
- 3194 - 3203
- publisher
- Springer
- external identifiers
-
- pmid:29460074
- scopus:85042173743
- ISSN
- 0938-7994
- DOI
- 10.1007/s00330-017-5297-7
- language
- English
- LU publication?
- yes
- id
- 0796596d-c77d-4248-9a24-cbd50badca63
- date added to LUP
- 2018-03-12 10:17:05
- date last changed
- 2024-07-22 13:59:55
@article{0796596d-c77d-4248-9a24-cbd50badca63, abstract = {{<p>Objectives: To compare breast density measured on digital breast tomosynthesis (DBT) (BI-RADS-based breast composition and fully-automatic estimation) and magnetic resonance imaging (MRI) (BI-RADS amount of fibroglandular tissue), and to evaluate the diagnostic performance in terms of sensitivity and specificity of DBT and MRI in a predominantly dense breast population. Methods: Between 2015 and 2016, 152 women with 103 breast malignancies, who underwent 3-T breast MRI and DBT within 2 months’ time, were enrolled in this study. Breast composition/fibroglandular tissue and findings on DBT (two readers) and MRI were reported using BI-RADS 5th edition. Digital mammography images were analysed for breast percent density (PD) using the Libra software tool. Results: A majority of women had dense breasts as categorised by breast composition c (heterogeneously dense) (68%) and d (extremely dense) (15%). The mean PD was 44% (range, 18-89%) and the correlation between breast composition and PD was r = 0.6. The diagnostic performance of MRI was significantly higher compared to DBT for one reader as described by the area under the receiver operating characteristic (ROC) curve (p = 0.004) and of borderline significance for the other reader (p = 0.052). Conclusions: MRI had higher diagnostic performance than DBT in a dense breast population in the tertiary setting. Key Points: • MRI had higher diagnostic performance than DBT in a dense breast population• Diagnostic performance of DBT was comparable to MRI in women with fatty breasts• MRI was superior to DBT in preoperative breast cancer size assessment</p>}}, author = {{Förnvik, Daniel and Kataoka, Masako and Iima, Mami and Ohashi, Akane and Kanao, Shotaro and Toi, Masakazu and Togashi, Kaori}}, issn = {{0938-7994}}, keywords = {{Breast cancer; Breast density; Diagnostic techniques and procedures; Digital breast tomosynthesis; Magnetic resonance imaging}}, language = {{eng}}, number = {{8}}, pages = {{3194--3203}}, publisher = {{Springer}}, series = {{European Radiology}}, title = {{The role of breast tomosynthesis in a predominantly dense breast population at a tertiary breast centre : breast density assessment and diagnostic performance in comparison with MRI}}, url = {{http://dx.doi.org/10.1007/s00330-017-5297-7}}, doi = {{10.1007/s00330-017-5297-7}}, volume = {{28}}, year = {{2018}}, }