Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

The association between plasma beta-hexosaminidase and its isoenzyme patterns and retinopathy in type 1 diabetes mellitus

Hultberg, Björn LU ; Isaksson, Anders LU ; Agardh, Elisabet LU and Agardh, Carl-David LU (1991) In Clinica Chimica Acta 196(2-3). p.177-183
Abstract
beta-Hexosaminidase and its isoenzyme patterns were investigated in plasma from patients with Type 1 diabetes mellitus. The patients were divided into three main groups matched for duration of diabetes: (a) proliferative retinopathy (b), progress of retinopathy within a two-year period (c) and with no background retinopathy. When all patients were compared to a reference group, a significant increase of plasma beta-hexosaminidase activity was found. Patients with proliferative retinopathy had significantly increased activity of plasma beta-hexosaminidase compared to the reference group but not compared to the other diabetic patients. The isoenzyme distribution was not different in any of the diabetic subgroups compared to the reference... (More)
beta-Hexosaminidase and its isoenzyme patterns were investigated in plasma from patients with Type 1 diabetes mellitus. The patients were divided into three main groups matched for duration of diabetes: (a) proliferative retinopathy (b), progress of retinopathy within a two-year period (c) and with no background retinopathy. When all patients were compared to a reference group, a significant increase of plasma beta-hexosaminidase activity was found. Patients with proliferative retinopathy had significantly increased activity of plasma beta-hexosaminidase compared to the reference group but not compared to the other diabetic patients. The isoenzyme distribution was not different in any of the diabetic subgroups compared to the reference group. It was also shown that various degrees of diabetic nephropathy did not influence total plasma Hex or the isoenzyme pattern. (Less)
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinica Chimica Acta
volume
196
issue
2-3
pages
177 - 183
publisher
Elsevier
external identifiers
  • pmid:1827617
  • scopus:0025974126
ISSN
0009-8981
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Unit on Vascular Diabetic Complications (013241510), Division of Clinical Chemistry and Pharmacology (013250300)
id
0881b901-c5c8-4df9-b994-850fb54feac5 (old id 1105842)
date added to LUP
2016-04-01 12:18:44
date last changed
2021-01-03 03:01:49
@article{0881b901-c5c8-4df9-b994-850fb54feac5,
  abstract     = {{beta-Hexosaminidase and its isoenzyme patterns were investigated in plasma from patients with Type 1 diabetes mellitus. The patients were divided into three main groups matched for duration of diabetes: (a) proliferative retinopathy (b), progress of retinopathy within a two-year period (c) and with no background retinopathy. When all patients were compared to a reference group, a significant increase of plasma beta-hexosaminidase activity was found. Patients with proliferative retinopathy had significantly increased activity of plasma beta-hexosaminidase compared to the reference group but not compared to the other diabetic patients. The isoenzyme distribution was not different in any of the diabetic subgroups compared to the reference group. It was also shown that various degrees of diabetic nephropathy did not influence total plasma Hex or the isoenzyme pattern.}},
  author       = {{Hultberg, Björn and Isaksson, Anders and Agardh, Elisabet and Agardh, Carl-David}},
  issn         = {{0009-8981}},
  language     = {{eng}},
  number       = {{2-3}},
  pages        = {{177--183}},
  publisher    = {{Elsevier}},
  series       = {{Clinica Chimica Acta}},
  title        = {{The association between plasma beta-hexosaminidase and its isoenzyme patterns and retinopathy in type 1 diabetes mellitus}},
  volume       = {{196}},
  year         = {{1991}},
}