Radioisotope evaluation of the esophageal remnant and the gastric conduit after gastric pull-up esophagectomy
(1999) In Surgery 125(3). p.297-303- Abstract
BACKGROUND: The act of swallowing after gastric pull-up esophagectomy has not been thoroughly investigated. The aim of this study was to evaluate deglutition in the esophageal remnant and in the gastric conduit in patients who have undergone this operation.
METHODS: The residual radionuclide activity was measured 15 seconds after a swallow in the esophageal remnant and at intervals up to a maximum of 120 minutes after a swallow in the gastric conduit. The scintigraphic rate of transit of a bolus in both areas was compared in patients who had anastomosis in the neck (n = 15) versus patients who had anastomosis in the chest (n = 19). Comparisons were also made between patients with and without symptoms of dysphagia. The... (More)
BACKGROUND: The act of swallowing after gastric pull-up esophagectomy has not been thoroughly investigated. The aim of this study was to evaluate deglutition in the esophageal remnant and in the gastric conduit in patients who have undergone this operation.
METHODS: The residual radionuclide activity was measured 15 seconds after a swallow in the esophageal remnant and at intervals up to a maximum of 120 minutes after a swallow in the gastric conduit. The scintigraphic rate of transit of a bolus in both areas was compared in patients who had anastomosis in the neck (n = 15) versus patients who had anastomosis in the chest (n = 19). Comparisons were also made between patients with and without symptoms of dysphagia. The scintigraphic measurements were also correlated with anastomotic diameters, measured with use of a volumetric balloon insufflation method, at 3, 6, and 12 months after operation.
RESULTS: There were no significant differences in esophageal residual radionuclide activity at 15 seconds after a swallow in the groups with anastomosis in the neck versus anastomosis in the chest, with 30% residual activity up to 12 months after operation in both groups (P = .24). In the patients as a whole the 50% gastric conduit emptying time of 44 to 61 minutes did not change during the first postoperative year (P = .12). There was no association between anastomotic diameter and residual activity in the remaining esophagus (P < .126). Moderate and severe dysphagia was reported in only a few patients, and there was no correlation between dysphagic symptoms and retention in the residual esophagus or slower emptying in the gastric conduit.
CONCLUSIONS: The amount of peristaltic activity in the remaining esophagus after esophagectomy with gastric replacement is unaffected by the level of the anastomosis. The gastric conduit empties slowly in all patients, and there is no correlation between the rate of emptying and either anastomotic diameter or symptoms of dysphagia.
(Less)
- author
- Johansson, Jan LU ; Sloth, M ; Bajc, M LU and Walther, B LU
- organization
- publishing date
- 1999-03
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Analysis of Variance, Anastomosis, Surgical/methods, Deglutition, Deglutition Disorders/diagnostic imaging, Esophagectomy/methods, Esophagus/diagnostic imaging, Humans, Peristalsis, Radionuclide Imaging, Stomach/diagnostic imaging, Time Factors
- in
- Surgery
- volume
- 125
- issue
- 3
- pages
- 7 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:10076614
- scopus:0032897296
- ISSN
- 0039-6060
- DOI
- 10.1016/S0039-6060(99)70240-0
- language
- English
- LU publication?
- yes
- id
- 088f280e-a2d7-4e5f-80f4-468cd90343fb
- date added to LUP
- 2019-05-26 18:59:19
- date last changed
- 2024-01-01 07:43:02
@article{088f280e-a2d7-4e5f-80f4-468cd90343fb,
abstract = {{<p>BACKGROUND: The act of swallowing after gastric pull-up esophagectomy has not been thoroughly investigated. The aim of this study was to evaluate deglutition in the esophageal remnant and in the gastric conduit in patients who have undergone this operation.</p><p>METHODS: The residual radionuclide activity was measured 15 seconds after a swallow in the esophageal remnant and at intervals up to a maximum of 120 minutes after a swallow in the gastric conduit. The scintigraphic rate of transit of a bolus in both areas was compared in patients who had anastomosis in the neck (n = 15) versus patients who had anastomosis in the chest (n = 19). Comparisons were also made between patients with and without symptoms of dysphagia. The scintigraphic measurements were also correlated with anastomotic diameters, measured with use of a volumetric balloon insufflation method, at 3, 6, and 12 months after operation.</p><p>RESULTS: There were no significant differences in esophageal residual radionuclide activity at 15 seconds after a swallow in the groups with anastomosis in the neck versus anastomosis in the chest, with 30% residual activity up to 12 months after operation in both groups (P = .24). In the patients as a whole the 50% gastric conduit emptying time of 44 to 61 minutes did not change during the first postoperative year (P = .12). There was no association between anastomotic diameter and residual activity in the remaining esophagus (P < .126). Moderate and severe dysphagia was reported in only a few patients, and there was no correlation between dysphagic symptoms and retention in the residual esophagus or slower emptying in the gastric conduit.</p><p>CONCLUSIONS: The amount of peristaltic activity in the remaining esophagus after esophagectomy with gastric replacement is unaffected by the level of the anastomosis. The gastric conduit empties slowly in all patients, and there is no correlation between the rate of emptying and either anastomotic diameter or symptoms of dysphagia.</p>}},
author = {{Johansson, Jan and Sloth, M and Bajc, M and Walther, B}},
issn = {{0039-6060}},
keywords = {{Analysis of Variance; Anastomosis, Surgical/methods; Deglutition; Deglutition Disorders/diagnostic imaging; Esophagectomy/methods; Esophagus/diagnostic imaging; Humans; Peristalsis; Radionuclide Imaging; Stomach/diagnostic imaging; Time Factors}},
language = {{eng}},
number = {{3}},
pages = {{297--303}},
publisher = {{Elsevier}},
series = {{Surgery}},
title = {{Radioisotope evaluation of the esophageal remnant and the gastric conduit after gastric pull-up esophagectomy}},
url = {{http://dx.doi.org/10.1016/S0039-6060(99)70240-0}},
doi = {{10.1016/S0039-6060(99)70240-0}},
volume = {{125}},
year = {{1999}},
}