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Proteomics : A new research area for the biomedical field

Malmström, Johan LU ; Malmström, Lars LU and Marko-Varga, György LU (2005) In Journal of Organ Dysfunction 1(1). p.83-94
Abstract

Proteomics, the detailed understanding of the role that proteins play in health and disease, is a necessary complement to genetic analysis. Rapid progress within the proteomics field has opened up possibilities for direct intervention in the medical and clinical area where diseases, disease progression and cause of disease can be investigated at a molecular level. This review introduces the proteomics field, illustrating the link to disease and organ dysfunctions, and the problem-solving progress currently ongoing in other research areas. The proteomics research field is progressing through developments in novel technology that have recently driven the biological interpretation of proteomics studies forward. A personal overview is... (More)

Proteomics, the detailed understanding of the role that proteins play in health and disease, is a necessary complement to genetic analysis. Rapid progress within the proteomics field has opened up possibilities for direct intervention in the medical and clinical area where diseases, disease progression and cause of disease can be investigated at a molecular level. This review introduces the proteomics field, illustrating the link to disease and organ dysfunctions, and the problem-solving progress currently ongoing in other research areas. The proteomics research field is progressing through developments in novel technology that have recently driven the biological interpretation of proteomics studies forward. A personal overview is presented with examples from the areas of clinical proteomics, tissue imaging and profiling, as well as examples of targeted proteomics studies.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
disease microenvironment, lung, mass spectrometry, multidimensional liquid phase separation
in
Journal of Organ Dysfunction
volume
1
issue
1
pages
12 pages
publisher
Informa Healthcare
external identifiers
  • scopus:33645757357
ISSN
1747-1060
DOI
10.1080/17471060500223910
language
English
LU publication?
yes
id
0898ba67-f9bc-4a68-a202-cd6cffdc6723
date added to LUP
2018-12-10 08:34:29
date last changed
2021-01-04 14:48:33
@article{0898ba67-f9bc-4a68-a202-cd6cffdc6723,
  abstract     = {<p>Proteomics, the detailed understanding of the role that proteins play in health and disease, is a necessary complement to genetic analysis. Rapid progress within the proteomics field has opened up possibilities for direct intervention in the medical and clinical area where diseases, disease progression and cause of disease can be investigated at a molecular level. This review introduces the proteomics field, illustrating the link to disease and organ dysfunctions, and the problem-solving progress currently ongoing in other research areas. The proteomics research field is progressing through developments in novel technology that have recently driven the biological interpretation of proteomics studies forward. A personal overview is presented with examples from the areas of clinical proteomics, tissue imaging and profiling, as well as examples of targeted proteomics studies.</p>},
  author       = {Malmström, Johan and Malmström, Lars and Marko-Varga, György},
  issn         = {1747-1060},
  language     = {eng},
  month        = {01},
  number       = {1},
  pages        = {83--94},
  publisher    = {Informa Healthcare},
  series       = {Journal of Organ Dysfunction},
  title        = {Proteomics : A new research area for the biomedical field},
  url          = {http://dx.doi.org/10.1080/17471060500223910},
  doi          = {10.1080/17471060500223910},
  volume       = {1},
  year         = {2005},
}