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Brain injury after cardiac arrest : pathophysiology, treatment, and prognosis

Sandroni, Claudio ; Cronberg, Tobias LU and Sekhon, Mypinder (2021) In Intensive Care Medicine 47(12). p.1393-1414
Abstract

Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This review describes the mechanisms of PCABI, its treatment options, its outcomes, and the suggested strategies for outcome prediction.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Brain, Cardiac arrest, Coma, EEG, Hypoxia-Ischemia, Prognostication
in
Intensive Care Medicine
volume
47
issue
12
pages
1393 - 1414
publisher
Springer
external identifiers
  • pmid:34705079
  • scopus:85117890102
ISSN
0342-4642
DOI
10.1007/s00134-021-06548-2
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2021, The Author(s).
id
099bf96c-30e0-48b0-b7b3-0e518fb7ba09
date added to LUP
2021-11-23 14:06:06
date last changed
2025-03-11 02:49:52
@article{099bf96c-30e0-48b0-b7b3-0e518fb7ba09,
  abstract     = {{<p>Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This review describes the mechanisms of PCABI, its treatment options, its outcomes, and the suggested strategies for outcome prediction.</p>}},
  author       = {{Sandroni, Claudio and Cronberg, Tobias and Sekhon, Mypinder}},
  issn         = {{0342-4642}},
  keywords     = {{Brain; Cardiac arrest; Coma; EEG; Hypoxia-Ischemia; Prognostication}},
  language     = {{eng}},
  number       = {{12}},
  pages        = {{1393--1414}},
  publisher    = {{Springer}},
  series       = {{Intensive Care Medicine}},
  title        = {{Brain injury after cardiac arrest : pathophysiology, treatment, and prognosis}},
  url          = {{http://dx.doi.org/10.1007/s00134-021-06548-2}},
  doi          = {{10.1007/s00134-021-06548-2}},
  volume       = {{47}},
  year         = {{2021}},
}