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Tramadol misuse in treatment-seeking adolescents and young adults with problematic substance use – Prediction of treatment retention

Almér Herrnsdorf, Eleonora ; Holmstedt, Alexander LU and Håkansson, Anders LU (2022) In Addictive Behaviors Reports 16.
Abstract

Non-medical prescription use of opioids (NMPUO) is a public health concern worldwide. Recently, tramadol misuse is increasing, but the systematic research of misuse of this specific opioid is limited. This study set out to assess the relationship between tramadol use and completion of treatment for substance use among adolescents and adults ≤ 25 years in an outpatient clinical setting. A retrospective cohort study of treatment outcome, expressed as “completion” or “non-completion” of treatment, was conducted in treatment-seeking adolescents with problematic substance use (n = 335). Data was extracted from Ung-DOK interviews, a semi-structured assessment instrument designed for adolescents with substance abuse. The study included all... (More)

Non-medical prescription use of opioids (NMPUO) is a public health concern worldwide. Recently, tramadol misuse is increasing, but the systematic research of misuse of this specific opioid is limited. This study set out to assess the relationship between tramadol use and completion of treatment for substance use among adolescents and adults ≤ 25 years in an outpatient clinical setting. A retrospective cohort study of treatment outcome, expressed as “completion” or “non-completion” of treatment, was conducted in treatment-seeking adolescents with problematic substance use (n = 335). Data was extracted from Ung-DOK interviews, a semi-structured assessment instrument designed for adolescents with substance abuse. The study included all treatment-seeking patients at an out-patient facility in 2014–2017. A total of 26% (n = 88) were tramadol users (life-time prevalence). Twenty percent (n = 66) of all treatments were non-completed. Tramadol users were significantly more likely than non-users to drop out of treatment (35% vs 15%, p < 0.001). In multivariate logistic regression, tramadol use and age 18 and above were factors significantly associated with non-completion. Tramadol use was statistically significantly associated with non-completion of treatment. Further research addressing treatment needs and treatment completion among tramadol users is needed.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adolescents, Non-medical prescription use of opioids, Retention, Substance use disorder, Tramadol
in
Addictive Behaviors Reports
volume
16
article number
100446
publisher
Elsevier
external identifiers
  • scopus:85134607978
  • pmid:35875347
ISSN
2352-8532
DOI
10.1016/j.abrep.2022.100446
language
English
LU publication?
yes
id
09f23c2c-b009-4987-ab67-923283083d35
date added to LUP
2022-09-02 14:10:22
date last changed
2025-03-20 23:42:16
@article{09f23c2c-b009-4987-ab67-923283083d35,
  abstract     = {{<p>Non-medical prescription use of opioids (NMPUO) is a public health concern worldwide. Recently, tramadol misuse is increasing, but the systematic research of misuse of this specific opioid is limited. This study set out to assess the relationship between tramadol use and completion of treatment for substance use among adolescents and adults ≤ 25 years in an outpatient clinical setting. A retrospective cohort study of treatment outcome, expressed as “completion” or “non-completion” of treatment, was conducted in treatment-seeking adolescents with problematic substance use (n = 335). Data was extracted from Ung-DOK interviews, a semi-structured assessment instrument designed for adolescents with substance abuse. The study included all treatment-seeking patients at an out-patient facility in 2014–2017. A total of 26% (n = 88) were tramadol users (life-time prevalence). Twenty percent (n = 66) of all treatments were non-completed. Tramadol users were significantly more likely than non-users to drop out of treatment (35% vs 15%, p &lt; 0.001). In multivariate logistic regression, tramadol use and age 18 and above were factors significantly associated with non-completion. Tramadol use was statistically significantly associated with non-completion of treatment. Further research addressing treatment needs and treatment completion among tramadol users is needed.</p>}},
  author       = {{Almér Herrnsdorf, Eleonora and Holmstedt, Alexander and Håkansson, Anders}},
  issn         = {{2352-8532}},
  keywords     = {{Adolescents; Non-medical prescription use of opioids; Retention; Substance use disorder; Tramadol}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Addictive Behaviors Reports}},
  title        = {{Tramadol misuse in treatment-seeking adolescents and young adults with problematic substance use – Prediction of treatment retention}},
  url          = {{http://dx.doi.org/10.1016/j.abrep.2022.100446}},
  doi          = {{10.1016/j.abrep.2022.100446}},
  volume       = {{16}},
  year         = {{2022}},
}