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Difference in Outcome Following Surgery for Native Aortic and Mitral Valve Infective Endocarditis

Kaartama, Tuukka ; Nozohoor, Shahab LU ; Johansson, Malin LU ; Sjögren, Johan LU ; Timane, Pedro and Ragnarsson, Sigurdur LU (2019) In The Thoracic and Cardiovascular Surgeon 67(8). p.652-658
Abstract

BACKGROUND:  We investigated differences in clinical presentation, microbiology, and short- and long-term results according to the affected valve in patients who underwent surgery for left-sided native valve infective endocarditis (IE).

METHODS:  This was a single-center retrospective study of 117 patients with isolated mitral valve IE (group M) and 140 patients with isolated aortic valve IE (group A) who underwent surgery between 1998 and 2015.

RESULTS:  The mean age of patients in group M was 62 ± 14 years, whereas in group A the patients were 56 ± 14 years old (p = 0.001). There were 61 females (52% of patients) in group M and 31 females (22% of patients) in group A (p < 0.001). Abscesses were more common in group A... (More)

BACKGROUND:  We investigated differences in clinical presentation, microbiology, and short- and long-term results according to the affected valve in patients who underwent surgery for left-sided native valve infective endocarditis (IE).

METHODS:  This was a single-center retrospective study of 117 patients with isolated mitral valve IE (group M) and 140 patients with isolated aortic valve IE (group A) who underwent surgery between 1998 and 2015.

RESULTS:  The mean age of patients in group M was 62 ± 14 years, whereas in group A the patients were 56 ± 14 years old (p = 0.001). There were 61 females (52% of patients) in group M and 31 females (22% of patients) in group A (p < 0.001). Abscesses were more common in group A than in group B. Staphylococcus aureus was more frequent in group M (47%, n = 55) than in group A (21%, n = 30; p < 0.001). The length of time from symptom onset to surgery was longer in group A than in group M, but the time from diagnosis to surgery was shorter in group A than in group M. Ninety-day mortality was similar in group M and group A in patients operated within 48 hours after diagnosis, but in patients who were operated more than 48 hours after diagnosis the 90-day mortality was 15% in group M and 3% in group A (p = 0.006).

CONCLUSION:  There were considerable differences in preoperative characteristics, microbiology, timing of surgery, and outcomes between patients who underwent surgery for isolated aortic valve IE and those who were operated for isolated mitral valve IE.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Thoracic and Cardiovascular Surgeon
volume
67
issue
8
pages
652 - 658
publisher
Georg Thieme Verlag
external identifiers
  • pmid:30500957
  • scopus:85076965370
ISSN
0171-6425
DOI
10.1055/s-0038-1676127
language
English
LU publication?
yes
additional info
Georg Thieme Verlag KG Stuttgart · New York.
id
0a47ec74-8758-4c3b-9868-4107f498007e
date added to LUP
2019-05-22 09:12:26
date last changed
2024-05-28 11:59:10
@article{0a47ec74-8758-4c3b-9868-4107f498007e,
  abstract     = {{<p>BACKGROUND:  We investigated differences in clinical presentation, microbiology, and short- and long-term results according to the affected valve in patients who underwent surgery for left-sided native valve infective endocarditis (IE).</p><p>METHODS:  This was a single-center retrospective study of 117 patients with isolated mitral valve IE (group M) and 140 patients with isolated aortic valve IE (group A) who underwent surgery between 1998 and 2015.</p><p>RESULTS:  The mean age of patients in group M was 62 ± 14 years, whereas in group A the patients were 56 ± 14 years old (p = 0.001). There were 61 females (52% of patients) in group M and 31 females (22% of patients) in group A (p &lt; 0.001). Abscesses were more common in group A than in group B. Staphylococcus aureus was more frequent in group M (47%, n = 55) than in group A (21%, n = 30; p &lt; 0.001). The length of time from symptom onset to surgery was longer in group A than in group M, but the time from diagnosis to surgery was shorter in group A than in group M. Ninety-day mortality was similar in group M and group A in patients operated within 48 hours after diagnosis, but in patients who were operated more than 48 hours after diagnosis the 90-day mortality was 15% in group M and 3% in group A (p = 0.006).</p><p>CONCLUSION:  There were considerable differences in preoperative characteristics, microbiology, timing of surgery, and outcomes between patients who underwent surgery for isolated aortic valve IE and those who were operated for isolated mitral valve IE.</p>}},
  author       = {{Kaartama, Tuukka and Nozohoor, Shahab and Johansson, Malin and Sjögren, Johan and Timane, Pedro and Ragnarsson, Sigurdur}},
  issn         = {{0171-6425}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{652--658}},
  publisher    = {{Georg Thieme Verlag}},
  series       = {{The Thoracic and Cardiovascular Surgeon}},
  title        = {{Difference in Outcome Following Surgery for Native Aortic and Mitral Valve Infective Endocarditis}},
  url          = {{http://dx.doi.org/10.1055/s-0038-1676127}},
  doi          = {{10.1055/s-0038-1676127}},
  volume       = {{67}},
  year         = {{2019}},
}