Benzylidene protected bis-MPA : A convenient dendrimer building block
(1998) In Tetrahedron Letters 39(20). p.3217-3220- Abstract
Benzylidene protected bis-MPA, 2,2-bis(hydroxymethyl)propanoic acid, was synthesised and evaluated as building block in the construction of dendrimers. It was found that the anhydride of benzylidene protected bis-MPA reacts with neopentylic alcohols to give high yields of acylated products. Purification is facilitated by the crystalline nature of most ester products. Deprotection by hydrogenolysis gives polyol dendrimers in good yields.
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- author
- Annby, Ulf ; Malmberg, Mats ; Pettersson, Bo and Rehnberg, Nicola LU
- publishing date
- 1998-05-14
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Tetrahedron Letters
- volume
- 39
- issue
- 20
- pages
- 4 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:0032516380
- ISSN
- 0040-4039
- DOI
- 10.1016/S0040-4039(98)00395-5
- language
- English
- LU publication?
- no
- id
- 0aac2bfd-0936-4219-ba18-45ba13b2f9be
- date added to LUP
- 2021-11-11 13:15:04
- date last changed
- 2022-02-02 01:16:15
@article{0aac2bfd-0936-4219-ba18-45ba13b2f9be, abstract = {{<p>Benzylidene protected bis-MPA, 2,2-bis(hydroxymethyl)propanoic acid, was synthesised and evaluated as building block in the construction of dendrimers. It was found that the anhydride of benzylidene protected bis-MPA reacts with neopentylic alcohols to give high yields of acylated products. Purification is facilitated by the crystalline nature of most ester products. Deprotection by hydrogenolysis gives polyol dendrimers in good yields.</p>}}, author = {{Annby, Ulf and Malmberg, Mats and Pettersson, Bo and Rehnberg, Nicola}}, issn = {{0040-4039}}, language = {{eng}}, month = {{05}}, number = {{20}}, pages = {{3217--3220}}, publisher = {{Elsevier}}, series = {{Tetrahedron Letters}}, title = {{Benzylidene protected bis-MPA : A convenient dendrimer building block}}, url = {{http://dx.doi.org/10.1016/S0040-4039(98)00395-5}}, doi = {{10.1016/S0040-4039(98)00395-5}}, volume = {{39}}, year = {{1998}}, }