How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?
(2012) In Biotechnology Journal 7(12). p.1522-1529- Abstract
- This report highlights the potential of measurement, monitoring, modeling and control ((MC)-C-3) methodologies in animal and human cell culture technology. In particular, state-of-the-art of (MC)-C-3 technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in (MC)-C-3 are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting (MC)-C-3 research toward the industrial interests. These include issues of importance for biotherapeutics production,... (More)
- This report highlights the potential of measurement, monitoring, modeling and control ((MC)-C-3) methodologies in animal and human cell culture technology. In particular, state-of-the-art of (MC)-C-3 technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in (MC)-C-3 are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting (MC)-C-3 research toward the industrial interests. These include issues of importance for biotherapeutics production, miniaturization of measurement techniques and modeling methods. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3367869
- author
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Biopharmaceuticals, Gene therapy, Mammalian cells, Stem cells, Viral, vectors
- in
- Biotechnology Journal
- volume
- 7
- issue
- 12
- pages
- 1522 - 1529
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000312032500013
- scopus:84870688374
- ISSN
- 1860-6768
- DOI
- 10.1002/biot.201200226
- language
- English
- LU publication?
- yes
- id
- 0ac7e068-72c5-4aa2-964e-ca90069ba8b4 (old id 3367869)
- date added to LUP
- 2016-04-01 09:49:56
- date last changed
- 2023-11-09 05:22:12
@article{0ac7e068-72c5-4aa2-964e-ca90069ba8b4, abstract = {{This report highlights the potential of measurement, monitoring, modeling and control ((MC)-C-3) methodologies in animal and human cell culture technology. In particular, state-of-the-art of (MC)-C-3 technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in (MC)-C-3 are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting (MC)-C-3 research toward the industrial interests. These include issues of importance for biotherapeutics production, miniaturization of measurement techniques and modeling methods.}}, author = {{Carrondo, Manuel J. T. and Alves, Paula M. and Carinhas, Nuno and Glassey, Jarka and Hesse, Friedemann and Merten, Otto-Wilhelm and Micheletti, Martina and Noll, Thomas and Oliveira, Rui and Reichl, Udo and Staby, Arne and Teixeira, Ana P. and Weichert, Henry and Mandenius, Carl-Fredrik}}, issn = {{1860-6768}}, keywords = {{Biopharmaceuticals; Gene therapy; Mammalian cells; Stem cells; Viral; vectors}}, language = {{eng}}, number = {{12}}, pages = {{1522--1529}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Biotechnology Journal}}, title = {{How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?}}, url = {{http://dx.doi.org/10.1002/biot.201200226}}, doi = {{10.1002/biot.201200226}}, volume = {{7}}, year = {{2012}}, }