Exploring the prevalence of undetected bradyarrhythmia in dementia with Lewy bodies
(2023) In Clinical autonomic research : official journal of the Clinical Autonomic Research Society 33(4). p.433-442- Abstract
PURPOSE: To explore the prevalence of undetected bradyarrhythmia in a cohort of people with dementia with Lewy bodies.
METHODS: Thirty participants diagnosed with dementia with Lewy bodies were enrolled from three memory clinics in southern Sweden between May 2021 and November 2022. None had a history of high-grade atrioventricular block or sick sinus syndrome. Each participant underwent orthostatic testing, cardiac [
123I]metaiodobenzylguanidine scintigraphy and 24-h ambulatory electrocardiographic monitoring. Concluding bradyarrhythmia diagnosis was obtained until the end of December 2022.
RESULTS: Thirteen participants (46.4%) had bradycardia at rest during orthostatic testing and four had an average heart rate... (More)
PURPOSE: To explore the prevalence of undetected bradyarrhythmia in a cohort of people with dementia with Lewy bodies.
METHODS: Thirty participants diagnosed with dementia with Lewy bodies were enrolled from three memory clinics in southern Sweden between May 2021 and November 2022. None had a history of high-grade atrioventricular block or sick sinus syndrome. Each participant underwent orthostatic testing, cardiac [
123I]metaiodobenzylguanidine scintigraphy and 24-h ambulatory electrocardiographic monitoring. Concluding bradyarrhythmia diagnosis was obtained until the end of December 2022.
RESULTS: Thirteen participants (46.4%) had bradycardia at rest during orthostatic testing and four had an average heart rate < 60 beats per minute during ambulatory electrocardiographic monitoring. Three participants (10.7%) received a diagnosis of sick sinus syndrome, of whom two received pacemaker implants to manage associated symptoms. None received a diagnosis of second- or third-degree atrioventricular block.
CONCLUSION: This report showed a high prevalence of sick sinus syndrome in a clinical cohort of people with dementia with Lewy bodies. Further research on the causes and consequences of sick sinus syndrome in dementia with Lewy bodies is thus warranted.
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- author
- Heyman, Isak LU ; Persson, Torbjörn ; Haglund, Mattias LU and Londos, Elisabet LU
- organization
- publishing date
- 2023-07-05
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical autonomic research : official journal of the Clinical Autonomic Research Society
- volume
- 33
- issue
- 4
- pages
- 433 - 442
- publisher
- Springer
- external identifiers
-
- scopus:85163925225
- pmid:37405543
- ISSN
- 1619-1560
- DOI
- 10.1007/s10286-023-00962-w
- language
- English
- LU publication?
- yes
- additional info
- © 2023. The Author(s).
- id
- 0c11c2c4-fa27-416b-82bb-d704e231ee39
- date added to LUP
- 2023-07-09 18:02:08
- date last changed
- 2024-04-19 23:17:24
@article{0c11c2c4-fa27-416b-82bb-d704e231ee39, abstract = {{<p>PURPOSE: To explore the prevalence of undetected bradyarrhythmia in a cohort of people with dementia with Lewy bodies.</p><p>METHODS: Thirty participants diagnosed with dementia with Lewy bodies were enrolled from three memory clinics in southern Sweden between May 2021 and November 2022. None had a history of high-grade atrioventricular block or sick sinus syndrome. Each participant underwent orthostatic testing, cardiac [<br> 123I]metaiodobenzylguanidine scintigraphy and 24-h ambulatory electrocardiographic monitoring. Concluding bradyarrhythmia diagnosis was obtained until the end of December 2022.<br> </p><p>RESULTS: Thirteen participants (46.4%) had bradycardia at rest during orthostatic testing and four had an average heart rate < 60 beats per minute during ambulatory electrocardiographic monitoring. Three participants (10.7%) received a diagnosis of sick sinus syndrome, of whom two received pacemaker implants to manage associated symptoms. None received a diagnosis of second- or third-degree atrioventricular block.</p><p>CONCLUSION: This report showed a high prevalence of sick sinus syndrome in a clinical cohort of people with dementia with Lewy bodies. Further research on the causes and consequences of sick sinus syndrome in dementia with Lewy bodies is thus warranted.</p>}}, author = {{Heyman, Isak and Persson, Torbjörn and Haglund, Mattias and Londos, Elisabet}}, issn = {{1619-1560}}, language = {{eng}}, month = {{07}}, number = {{4}}, pages = {{433--442}}, publisher = {{Springer}}, series = {{Clinical autonomic research : official journal of the Clinical Autonomic Research Society}}, title = {{Exploring the prevalence of undetected bradyarrhythmia in dementia with Lewy bodies}}, url = {{http://dx.doi.org/10.1007/s10286-023-00962-w}}, doi = {{10.1007/s10286-023-00962-w}}, volume = {{33}}, year = {{2023}}, }