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Hudlymfom – ovanlig sjukdom ofta med lång tid till diagnos

Belfrage, Emma LU ; Relander, Thomas LU and Brauner, Hanna (2021) In Lakartidningen 118.
Abstract

Primary cutaneous lymphoma is a heterogeneous group of diseases where the malignant lymphocytes are primarily present in the skin at the time of diagnosis. The most common type of primary cutaneous lymphoma is mycosis fungoides. Early stages of mycosis fungoides present with flat or slightly elevated red skin lesions and can resemble eczema or psoriasis. In advanced stages erythrodermia or skin tumors can develop. For many patients with mycosis fungoides effective albeit not curative treatment is available. Large randomized treatment studies for mycosis fungoides are largely lacking, which makes decisions on treatment strategy difficult. The new national clinical guidelines will hopefully enable more equal care for patients with mycosis... (More)

Primary cutaneous lymphoma is a heterogeneous group of diseases where the malignant lymphocytes are primarily present in the skin at the time of diagnosis. The most common type of primary cutaneous lymphoma is mycosis fungoides. Early stages of mycosis fungoides present with flat or slightly elevated red skin lesions and can resemble eczema or psoriasis. In advanced stages erythrodermia or skin tumors can develop. For many patients with mycosis fungoides effective albeit not curative treatment is available. Large randomized treatment studies for mycosis fungoides are largely lacking, which makes decisions on treatment strategy difficult. The new national clinical guidelines will hopefully enable more equal care for patients with mycosis fungoides and other types of primary cutaneous lymphoma in Sweden.

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Abstract (Swedish)
Hudlymfom är en heterogen grupp av sjukdomar där lymfomcellerna primärt uppträder i huden. T-cellslymfom utgör 70–80 procent och B-cellslymfom 20–30 procent av de primära kutana lymfomen. Mycosis fungoides är det vanligaste hudlymfomet.Den kliniska bilden vid mycosis fungoides kan vara svårtolkad och kan likna vanliga hudsjukdomar som psoriasis och eksem. De histomorfologiska förändringarna vid tidig mycosis fungoides kan vara diskreta, och ofta måste upprepade hudbiopsier tas över tid för att diagnosen ska kunna ställas. Det finns ett nytt nationellt vårdprogram för hudlymfom från Regionala cancercentrum i samverkan (RCC) som ger stöd vid utredning och behandling.
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author
; and
organization
alternative title
New national treatment guidelines for primary cutaneous lymphoma
publishing date
type
Contribution to journal
publication status
published
subject
in
Lakartidningen
volume
118
publisher
Swedish Medical Association
external identifiers
  • pmid:34498247
  • scopus:85115959318
ISSN
0023-7205
language
Swedish
LU publication?
yes
additional info
Funding Information: We thank Dr. K,-D. Kniffki for critically reading the manuscript and helpful suggestions. The secretarial help of Mrs. C. Scheuerbrandt is greatly acknowledged. This work was supported by the Deutsche Forschungsgemeinsehaft, Sonderforschungsbereich 'Hirnforschung und Sinnesphysiologie' (SFB 70)•
id
0e157738-0a5d-4c34-a93e-b9efcfb31e41
date added to LUP
2021-10-21 15:42:15
date last changed
2024-06-01 18:04:00
@article{0e157738-0a5d-4c34-a93e-b9efcfb31e41,
  abstract     = {{<p>Primary cutaneous lymphoma is a heterogeneous group of diseases where the malignant lymphocytes are primarily present in the skin at the time of diagnosis. The most common type of primary cutaneous lymphoma is mycosis fungoides. Early stages of mycosis fungoides present with flat or slightly elevated red skin lesions and can resemble eczema or psoriasis. In advanced stages erythrodermia or skin tumors can develop. For many patients with mycosis fungoides effective albeit not curative treatment is available. Large randomized treatment studies for mycosis fungoides are largely lacking, which makes decisions on treatment strategy difficult. The new national clinical guidelines will hopefully enable more equal care for patients with mycosis fungoides and other types of primary cutaneous lymphoma in Sweden.</p>}},
  author       = {{Belfrage, Emma and Relander, Thomas and Brauner, Hanna}},
  issn         = {{0023-7205}},
  language     = {{swe}},
  month        = {{08}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Lakartidningen}},
  title        = {{Hudlymfom – ovanlig sjukdom ofta med lång tid till diagnos}},
  volume       = {{118}},
  year         = {{2021}},
}