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Central venous catheter-related complications in hematologic patients : An observational study

Rockholt, Mika M LU orcid ; Thorarinsdottir, Hulda R LU ; Lazarevic, Vladimir LU ; Rundgren, Malin LU and Kander, Thomas LU orcid (2022) In Acta Anaesthesiologica Scandinavica 66(4). p.473-482
Abstract

BACKGROUND: The frequency of central venous catheter (CVC) related complications in hematological patients has previously been studied but some uncertainty remains. Therefore, this observational cohort study was designed primarily to investigate mechanical and infectious complications related to CVC insertion in hematological patients and secondarily, to identify factors associated with these complications.

METHODS: Documented data on CVC insertions in all adult hematology patients who received a CVC from 2013 to 2019 at a University Hospital in Sweden, were retrospectively collected.

RESULTS: A total of 589 CVC insertions in 387 patients were included. The prevalence of moderate and severe mechanical complications,... (More)

BACKGROUND: The frequency of central venous catheter (CVC) related complications in hematological patients has previously been studied but some uncertainty remains. Therefore, this observational cohort study was designed primarily to investigate mechanical and infectious complications related to CVC insertion in hematological patients and secondarily, to identify factors associated with these complications.

METHODS: Documented data on CVC insertions in all adult hematology patients who received a CVC from 2013 to 2019 at a University Hospital in Sweden, were retrospectively collected.

RESULTS: A total of 589 CVC insertions in 387 patients were included. The prevalence of moderate and severe mechanical complications, predominantly comprising grade 2-4 bleeding, was 11%. Pre-procedural coagulopathy, number of needle passes and arterial puncture were all independently associated with grade 2-4 bleeding. The incidence of suspected catheter-related infections (sCRI) was 3.7/1000 catheter days. Higher body-mass index and male gender were independently associated with sCRI.

CONCLUSIONS: Patients with hematological malignancies have a high risk of both grade 2-4 bleeding and sCRI after CVC insertion. This underlines the importance of optimizing the conditions at the insertion and also of daily inspections, evaluation of future needs and extra precautions to avoid sCRI in these susceptible patients.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Anaesthesiologica Scandinavica
volume
66
issue
4
pages
473 - 482
publisher
Wiley-Blackwell
external identifiers
  • pmid:34907524
  • scopus:85121657742
  • pmid:34907524
ISSN
0001-5172
DOI
10.1111/aas.14020
language
English
LU publication?
yes
id
0e69f4a7-63b3-4983-8abd-69ec924a598a
date added to LUP
2021-12-16 16:18:24
date last changed
2024-06-15 22:58:23
@article{0e69f4a7-63b3-4983-8abd-69ec924a598a,
  abstract     = {{<p>BACKGROUND: The frequency of central venous catheter (CVC) related complications in hematological patients has previously been studied but some uncertainty remains. Therefore, this observational cohort study was designed primarily to investigate mechanical and infectious complications related to CVC insertion in hematological patients and secondarily, to identify factors associated with these complications.</p><p>METHODS: Documented data on CVC insertions in all adult hematology patients who received a CVC from 2013 to 2019 at a University Hospital in Sweden, were retrospectively collected.</p><p>RESULTS: A total of 589 CVC insertions in 387 patients were included. The prevalence of moderate and severe mechanical complications, predominantly comprising grade 2-4 bleeding, was 11%. Pre-procedural coagulopathy, number of needle passes and arterial puncture were all independently associated with grade 2-4 bleeding. The incidence of suspected catheter-related infections (sCRI) was 3.7/1000 catheter days. Higher body-mass index and male gender were independently associated with sCRI.</p><p>CONCLUSIONS: Patients with hematological malignancies have a high risk of both grade 2-4 bleeding and sCRI after CVC insertion. This underlines the importance of optimizing the conditions at the insertion and also of daily inspections, evaluation of future needs and extra precautions to avoid sCRI in these susceptible patients.</p>}},
  author       = {{Rockholt, Mika M and Thorarinsdottir, Hulda R and Lazarevic, Vladimir and Rundgren, Malin and Kander, Thomas}},
  issn         = {{0001-5172}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{473--482}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Anaesthesiologica Scandinavica}},
  title        = {{Central venous catheter-related complications in hematologic patients : An observational study}},
  url          = {{http://dx.doi.org/10.1111/aas.14020}},
  doi          = {{10.1111/aas.14020}},
  volume       = {{66}},
  year         = {{2022}},
}