Breast percent density : Estimation on digital mammograms and central tomosynthesis projections
(2009) In Radiology 252(1). p.40-49- Abstract
Purpose: To evaluate inter- and intrareader agreement in breast percent density (PD) estimation on clinical digital mammograms and central digital breast tomosynthesis (DBT) projection images. Materials and Methods: This HIPAA-compliant study had institutional review board approval; all patients provided informed consent. Breast PD estimation was performed on the basis of anonymized digital mammograms and central DBT projections in 39 women (mean age, 51 years; range, 31-80 years). All women had recently detected abnormalities or biopsyproved cancers. PD was estimated by three experienced readers on the mediolateral oblique views of the contralateral breasts by using software; each reader repeated the estimation after 2 months. Spearman... (More)
Purpose: To evaluate inter- and intrareader agreement in breast percent density (PD) estimation on clinical digital mammograms and central digital breast tomosynthesis (DBT) projection images. Materials and Methods: This HIPAA-compliant study had institutional review board approval; all patients provided informed consent. Breast PD estimation was performed on the basis of anonymized digital mammograms and central DBT projections in 39 women (mean age, 51 years; range, 31-80 years). All women had recently detected abnormalities or biopsyproved cancers. PD was estimated by three experienced readers on the mediolateral oblique views of the contralateral breasts by using software; each reader repeated the estimation after 2 months. Spearman correlations of interand intrareader and intermodality PD estimates, as well as κ statistics between categoric PD estimates, were computed. Results: High correlation (ρ = 0.91) was observed between PD estimates on digital mammograms and those on central DBT projections, averaged over all estimations; the corresponding κ coefficient (0.79) indicated substantial agreement. Mean interreader agreement for PD estimation on central DBT projections (ρ = 0.85 ± 0.05 [standard deviation]) was significantly higher (P < .01) than that for PD estimation on digital mammograms (ρ = 0.75 ± 0.05); the corresponding κ coefficients indicated substantial (κ = 0.65 ± 0.12) and moderate (κ = 0.55 ± 0.14) agreement for central DBT projections and digital mammograms, respectively. Conclusion: High correlation between PD estimates on digital mammograms and those on central DBT projections suggests the latter could be used until a method for PD estimation based on three-dimensional reconstructed images is introduced. Moreover, clinical PD estimation is possible with reduced radiation dose, as each DBT projection was acquired by using about 22% of the dose for a single mammographic projection.
(Less)
- author
- Bakic, Predrag R. LU ; Carton, Ann Katherine ; Kontos, Despina ; Zhang, Cuiping ; Troxel, Andrea B. and Maidment, Andrew D.A.
- publishing date
- 2009-07
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Radiology
- volume
- 252
- issue
- 1
- pages
- 10 pages
- publisher
- Radiological Society of North America
- external identifiers
-
- pmid:19420321
- scopus:67650097301
- ISSN
- 0033-8419
- DOI
- 10.1148/radiol.2521081621
- language
- English
- LU publication?
- no
- id
- 0e9e8ab5-a349-4858-aae4-2444348e6d7d
- date added to LUP
- 2020-11-07 13:17:35
- date last changed
- 2024-05-15 21:55:00
@article{0e9e8ab5-a349-4858-aae4-2444348e6d7d,
abstract = {{<p>Purpose: To evaluate inter- and intrareader agreement in breast percent density (PD) estimation on clinical digital mammograms and central digital breast tomosynthesis (DBT) projection images. Materials and Methods: This HIPAA-compliant study had institutional review board approval; all patients provided informed consent. Breast PD estimation was performed on the basis of anonymized digital mammograms and central DBT projections in 39 women (mean age, 51 years; range, 31-80 years). All women had recently detected abnormalities or biopsyproved cancers. PD was estimated by three experienced readers on the mediolateral oblique views of the contralateral breasts by using software; each reader repeated the estimation after 2 months. Spearman correlations of interand intrareader and intermodality PD estimates, as well as κ statistics between categoric PD estimates, were computed. Results: High correlation (ρ = 0.91) was observed between PD estimates on digital mammograms and those on central DBT projections, averaged over all estimations; the corresponding κ coefficient (0.79) indicated substantial agreement. Mean interreader agreement for PD estimation on central DBT projections (ρ = 0.85 ± 0.05 [standard deviation]) was significantly higher (P < .01) than that for PD estimation on digital mammograms (ρ = 0.75 ± 0.05); the corresponding κ coefficients indicated substantial (κ = 0.65 ± 0.12) and moderate (κ = 0.55 ± 0.14) agreement for central DBT projections and digital mammograms, respectively. Conclusion: High correlation between PD estimates on digital mammograms and those on central DBT projections suggests the latter could be used until a method for PD estimation based on three-dimensional reconstructed images is introduced. Moreover, clinical PD estimation is possible with reduced radiation dose, as each DBT projection was acquired by using about 22% of the dose for a single mammographic projection.</p>}},
author = {{Bakic, Predrag R. and Carton, Ann Katherine and Kontos, Despina and Zhang, Cuiping and Troxel, Andrea B. and Maidment, Andrew D.A.}},
issn = {{0033-8419}},
language = {{eng}},
number = {{1}},
pages = {{40--49}},
publisher = {{Radiological Society of North America}},
series = {{Radiology}},
title = {{Breast percent density : Estimation on digital mammograms and central tomosynthesis projections}},
url = {{http://dx.doi.org/10.1148/radiol.2521081621}},
doi = {{10.1148/radiol.2521081621}},
volume = {{252}},
year = {{2009}},
}