Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

The Swedish sleep apnea registry (SESAR) cohort – “Real world data” on a national level

Grote, Ludger ; Jonzon, Yvonne Asp ; Barta, Peter ; Murto, Tarmo ; Nilsson, Zarita ; Nygren, Anna ; Theorell-Haglöw, Jenny ; Sunnergren, Ola ; Ulander, Martin and Ekström, Magnus LU orcid , et al. (2024) In Sleep Medicine 124. p.362-370
Abstract

Introduction: The Swedish Sleep Apnea Registry (SESAR) collects clinical data from individual obstructive sleep apnea (OSA) patients since 2010. SESAR has recently been integrated with additional national healthcare data. The current analysis presents the SESAR structure and representative clinical data of a national sleep apnea cohort. Methods: Clinical data from unselected patients with a diagnosis of OSA are submitted to the SESAR registry. 48 sleep centers report data from diagnosis, treatment starts with Continuous Positive Airway Pressure (CPAP), oral devices (OD), and Upper Airway Surgery (UAS). Data from follow-up are included. SESAR is linked to mandatory national healthcare data (mortality, comorbidities, procedures,... (More)

Introduction: The Swedish Sleep Apnea Registry (SESAR) collects clinical data from individual obstructive sleep apnea (OSA) patients since 2010. SESAR has recently been integrated with additional national healthcare data. The current analysis presents the SESAR structure and representative clinical data of a national sleep apnea cohort. Methods: Clinical data from unselected patients with a diagnosis of OSA are submitted to the SESAR registry. 48 sleep centers report data from diagnosis, treatment starts with Continuous Positive Airway Pressure (CPAP), oral devices (OD), and Upper Airway Surgery (UAS). Data from follow-up are included. SESAR is linked to mandatory national healthcare data (mortality, comorbidities, procedures, prescriptions) and diagnosis-specific quality registries (e.g. stroke, heart failure, diabetes) within the DISCOVERY project. Results: 83,404 OSA patients have been reported during the diagnostic workup (age 55.4 ± 14.1 years, BMI 30.8 ± 6.5 kg/m2, AHI 25.8 ± 21.6n/h, respectively). At least one cardiometabolic and respiratory comorbidity is recognized in 57 % of female and 53 % of male OSA patients with a linear increase across OSA severity. In 54,468, 7,797, and 390 patients, start of CPAP, OD or UAS treatment is reported, respectively. OD patients have 4 units lower BMI and 10 units lower AHI compared to patients started on CPAP. UAS patients are characterized by 10 years lower age. The degree of daytime sleepiness is comparable between treatment groups with mean Epworth Sleepiness Scale Scores between 9 and 10. Conclusion: SESAR is introduced as a large national registry of OSA patients. SESAR provides a useful tool to highlight OSA management and to perform relevant outcome research.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
CPAP, Disease management, Gender, Guideline, Obstructive sleep apnea, Oral device, Phenotypes, Prospective analysis
in
Sleep Medicine
volume
124
pages
9 pages
publisher
Elsevier
external identifiers
  • scopus:85205547381
  • pmid:39378545
ISSN
1389-9457
DOI
10.1016/j.sleep.2024.09.039
language
English
LU publication?
yes
id
0f304a09-ac56-411b-b2ac-0fb73e046dd2
date added to LUP
2024-11-27 17:41:55
date last changed
2025-01-22 22:41:08
@article{0f304a09-ac56-411b-b2ac-0fb73e046dd2,
  abstract     = {{<p>Introduction: The Swedish Sleep Apnea Registry (SESAR) collects clinical data from individual obstructive sleep apnea (OSA) patients since 2010. SESAR has recently been integrated with additional national healthcare data. The current analysis presents the SESAR structure and representative clinical data of a national sleep apnea cohort. Methods: Clinical data from unselected patients with a diagnosis of OSA are submitted to the SESAR registry. 48 sleep centers report data from diagnosis, treatment starts with Continuous Positive Airway Pressure (CPAP), oral devices (OD), and Upper Airway Surgery (UAS). Data from follow-up are included. SESAR is linked to mandatory national healthcare data (mortality, comorbidities, procedures, prescriptions) and diagnosis-specific quality registries (e.g. stroke, heart failure, diabetes) within the DISCOVERY project. Results: 83,404 OSA patients have been reported during the diagnostic workup (age 55.4 ± 14.1 years, BMI 30.8 ± 6.5 kg/m<sup>2</sup>, AHI 25.8 ± 21.6n/h, respectively). At least one cardiometabolic and respiratory comorbidity is recognized in 57 % of female and 53 % of male OSA patients with a linear increase across OSA severity. In 54,468, 7,797, and 390 patients, start of CPAP, OD or UAS treatment is reported, respectively. OD patients have 4 units lower BMI and 10 units lower AHI compared to patients started on CPAP. UAS patients are characterized by 10 years lower age. The degree of daytime sleepiness is comparable between treatment groups with mean Epworth Sleepiness Scale Scores between 9 and 10. Conclusion: SESAR is introduced as a large national registry of OSA patients. SESAR provides a useful tool to highlight OSA management and to perform relevant outcome research.</p>}},
  author       = {{Grote, Ludger and Jonzon, Yvonne Asp and Barta, Peter and Murto, Tarmo and Nilsson, Zarita and Nygren, Anna and Theorell-Haglöw, Jenny and Sunnergren, Ola and Ulander, Martin and Ekström, Magnus and Palm, Andreas and Hedner, Jan}},
  issn         = {{1389-9457}},
  keywords     = {{CPAP; Disease management; Gender; Guideline; Obstructive sleep apnea; Oral device; Phenotypes; Prospective analysis}},
  language     = {{eng}},
  pages        = {{362--370}},
  publisher    = {{Elsevier}},
  series       = {{Sleep Medicine}},
  title        = {{The Swedish sleep apnea registry (SESAR) cohort – “Real world data” on a national level}},
  url          = {{http://dx.doi.org/10.1016/j.sleep.2024.09.039}},
  doi          = {{10.1016/j.sleep.2024.09.039}},
  volume       = {{124}},
  year         = {{2024}},
}