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Agreement of the modified Medical Research Council and New York Heart Association scales for assessing the impact of self-rated breathlessness in cardiopulmonary disease

Ahmadi, Zainab LU ; Igelström, Helena ; Sandberg, Jacob LU orcid ; Sundh, Josefin ; Sköld, Magnus ; Janson, Christer ; Blomberg, Anders ; Bornefalk, Hans ; Bornefalk-Hermansson, Anna and Ekström, Magnus LU orcid (2022) In ERJ open research 8(1).
Abstract

Background: The functional impact of breathlessness is assessed using the modified Medical Research Council (mMRC) scale for chronic respiratory disease and with the New York Heart Association Functional Classification (NYHA) scale for heart failure. We evaluated agreement between the scales and their concurrent validity with other clinically relevant patient-reported outcomes in cardiorespiratory disease.

Methods: Outpatients with stable chronic respiratory disease or heart failure were recruited. Agreement between the mMRC and NYHA scales was analysed using Cramér's V and Kendall's tau B tests. Concurrent validity was evaluated using correlations with clinically relevant measures of breathlessness, anxiety, depression, and... (More)

Background: The functional impact of breathlessness is assessed using the modified Medical Research Council (mMRC) scale for chronic respiratory disease and with the New York Heart Association Functional Classification (NYHA) scale for heart failure. We evaluated agreement between the scales and their concurrent validity with other clinically relevant patient-reported outcomes in cardiorespiratory disease.

Methods: Outpatients with stable chronic respiratory disease or heart failure were recruited. Agreement between the mMRC and NYHA scales was analysed using Cramér's V and Kendall's tau B tests. Concurrent validity was evaluated using correlations with clinically relevant measures of breathlessness, anxiety, depression, and health-related quality of life. Analyses were conducted for all participants and separately in chronic obstructive pulmonary disease (COPD) and heart failure.

Results: In a total of 182 participants with cardiorespiratory disease, the agreement between the mMRC and NYHA scales was moderate (Cramér's V: 0.46; Kendall's tau B: 0.57) with similar results for COPD (Cramér's V: 0.46; Kendall's tau B: 0.66) and heart failure (Cramér's V: 0.46; Kendall's tau B: 0.67). In the total population, the scales correlated in similar ways to other patient-reported outcomes.

Conclusion: In outpatients with cardiorespiratory disease, the mMRC and NYHA scales show moderate to strong correlations and similar associations with other patient-reported outcomes. This supports that the scales are comparable when assessing the impact of breathlessness on function and patient-reported outcomes.

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author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
ERJ open research
volume
8
issue
1
pages
7 pages
publisher
European Respiratory Society
external identifiers
  • scopus:85127727527
  • pmid:35083321
ISSN
2312-0541
DOI
10.1183/23120541.00460-2021
language
English
LU publication?
yes
additional info
Copyright ©The authors 2022.
id
0f719730-af13-4af2-90ab-043424aa098e
date added to LUP
2022-02-08 13:44:45
date last changed
2024-06-13 16:47:34
@article{0f719730-af13-4af2-90ab-043424aa098e,
  abstract     = {{<p>Background: The functional impact of breathlessness is assessed using the modified Medical Research Council (mMRC) scale for chronic respiratory disease and with the New York Heart Association Functional Classification (NYHA) scale for heart failure. We evaluated agreement between the scales and their concurrent validity with other clinically relevant patient-reported outcomes in cardiorespiratory disease.</p><p>Methods: Outpatients with stable chronic respiratory disease or heart failure were recruited. Agreement between the mMRC and NYHA scales was analysed using Cramér's V and Kendall's tau B tests. Concurrent validity was evaluated using correlations with clinically relevant measures of breathlessness, anxiety, depression, and health-related quality of life. Analyses were conducted for all participants and separately in chronic obstructive pulmonary disease (COPD) and heart failure.</p><p>Results: In a total of 182 participants with cardiorespiratory disease, the agreement between the mMRC and NYHA scales was moderate (Cramér's V: 0.46; Kendall's tau B: 0.57) with similar results for COPD (Cramér's V: 0.46; Kendall's tau B: 0.66) and heart failure (Cramér's V: 0.46; Kendall's tau B: 0.67). In the total population, the scales correlated in similar ways to other patient-reported outcomes.</p><p>Conclusion: In outpatients with cardiorespiratory disease, the mMRC and NYHA scales show moderate to strong correlations and similar associations with other patient-reported outcomes. This supports that the scales are comparable when assessing the impact of breathlessness on function and patient-reported outcomes.</p>}},
  author       = {{Ahmadi, Zainab and Igelström, Helena and Sandberg, Jacob and Sundh, Josefin and Sköld, Magnus and Janson, Christer and Blomberg, Anders and Bornefalk, Hans and Bornefalk-Hermansson, Anna and Ekström, Magnus}},
  issn         = {{2312-0541}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{European Respiratory Society}},
  series       = {{ERJ open research}},
  title        = {{Agreement of the modified Medical Research Council and New York Heart Association scales for assessing the impact of self-rated breathlessness in cardiopulmonary disease}},
  url          = {{http://dx.doi.org/10.1183/23120541.00460-2021}},
  doi          = {{10.1183/23120541.00460-2021}},
  volume       = {{8}},
  year         = {{2022}},
}