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Rationale for multiple risk intervention: the need to move from theory to practice.

Erhardt, Leif RW LU (2007) In Vascular Health and Risk Management 3(6). p.985-997
Abstract
Incidence of cardiovascular (CV) and metabolic disease is increasing, in parallel with associated risk factors. These factors, such as low-density lipoprotein (LDL)-cholesterol, elevated blood pressure, obesity, and insulin resistance have a continuous, progressive impact on total CV risk, with higher levels and numbers of factors translating into greater risk. Evaluation of all known modifiable risk factors, to provide a detailed total CV disease (CVD) and metabolic risk-status profile is therefore necessary to ensure appropriate treatment of each factor within the context of a multifactorial, global approach to prevention of CVD and metabolic disease. Effective and well-tolerated pharmacotherapies are available for the treatment of... (More)
Incidence of cardiovascular (CV) and metabolic disease is increasing, in parallel with associated risk factors. These factors, such as low-density lipoprotein (LDL)-cholesterol, elevated blood pressure, obesity, and insulin resistance have a continuous, progressive impact on total CV risk, with higher levels and numbers of factors translating into greater risk. Evaluation of all known modifiable risk factors, to provide a detailed total CV disease (CVD) and metabolic risk-status profile is therefore necessary to ensure appropriate treatment of each factor within the context of a multifactorial, global approach to prevention of CVD and metabolic disease. Effective and well-tolerated pharmacotherapies are available for the treatment of risk-factors. Realization of the potential health and economic benefits of effective risk factor management requires improved risk factor screening, early and aggressive treatment, improved public health support (ie, education and guidelines), and appropriate therapeutic interventions based on current guidelines and accurate risk assessment. Patient compliance and persistence to available therapies is also necessary for successful modulation of CVD risk. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Vascular Health and Risk Management
volume
3
issue
6
pages
985 - 997
publisher
Dove Press
external identifiers
  • pmid:18200817
  • scopus:38149044844
ISSN
1178-2048
language
English
LU publication?
yes
id
056365c5-8ae2-41ca-ae8b-568406b463fc (old id 1021323)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18200817?dopt=Abstract
date added to LUP
2008-02-11 12:01:45
date last changed
2017-01-01 07:31:01
@article{056365c5-8ae2-41ca-ae8b-568406b463fc,
  abstract     = {Incidence of cardiovascular (CV) and metabolic disease is increasing, in parallel with associated risk factors. These factors, such as low-density lipoprotein (LDL)-cholesterol, elevated blood pressure, obesity, and insulin resistance have a continuous, progressive impact on total CV risk, with higher levels and numbers of factors translating into greater risk. Evaluation of all known modifiable risk factors, to provide a detailed total CV disease (CVD) and metabolic risk-status profile is therefore necessary to ensure appropriate treatment of each factor within the context of a multifactorial, global approach to prevention of CVD and metabolic disease. Effective and well-tolerated pharmacotherapies are available for the treatment of risk-factors. Realization of the potential health and economic benefits of effective risk factor management requires improved risk factor screening, early and aggressive treatment, improved public health support (ie, education and guidelines), and appropriate therapeutic interventions based on current guidelines and accurate risk assessment. Patient compliance and persistence to available therapies is also necessary for successful modulation of CVD risk.},
  author       = {Erhardt, Leif RW},
  issn         = {1178-2048},
  language     = {eng},
  number       = {6},
  pages        = {985--997},
  publisher    = {Dove Press},
  series       = {Vascular Health and Risk Management},
  title        = {Rationale for multiple risk intervention: the need to move from theory to practice.},
  volume       = {3},
  year         = {2007},
}