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Decoration of amyloid fibrils with luminescent conjugated polymers

Herland, Anna; Thomsson, Daniel LU ; Mirzov, Oleg LU ; Scheblykin, Ivan LU and Inganäs, Olle (2008) In Journal of Materials Chemistry 18. p.126-132
Abstract
In this work we report the coating of a biological template with a polar, but uncharged,luminescent conjugated polymer, soluble in organic solvents but not in water, to produce a nanowire. Amyloid fibrils from bovine insulin were decorated with an alternating polyfluorene derivative. Decorated fibrils were partially aligned on hydrophobic surfaces as separate and

bundled fibrils, by means of molecular combing. The single molecule spectroscopy technique utilizing excitation by rotating linearly polarized light and fluorescence detection through a rotating polarizer showed a high degree of anisotropy of the polymer chains on the individual fibrils. The high degree of polarization indicated highly oriented polymer chains with the... (More)
In this work we report the coating of a biological template with a polar, but uncharged,luminescent conjugated polymer, soluble in organic solvents but not in water, to produce a nanowire. Amyloid fibrils from bovine insulin were decorated with an alternating polyfluorene derivative. Decorated fibrils were partially aligned on hydrophobic surfaces as separate and

bundled fibrils, by means of molecular combing. The single molecule spectroscopy technique utilizing excitation by rotating linearly polarized light and fluorescence detection through a rotating polarizer showed a high degree of anisotropy of the polymer chains on the individual fibrils. The high degree of polarization indicated highly oriented polymer chains with the preferential orientation of the polymer backbone along the fibrils. The anisotropy ratios are

comparable with those of well-oriented polymer chains in films. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Materials Chemistry
volume
18
pages
126 - 132
publisher
Royal Society of Chemistry
external identifiers
  • wos:000251580400016
  • scopus:37149043452
ISSN
1364-5501
DOI
10.1039/b712829k
language
English
LU publication?
yes
id
96074020-2fd1-4c35-988a-a620dbdb5569 (old id 1025154)
date added to LUP
2008-02-14 17:07:51
date last changed
2017-01-01 04:25:37
@article{96074020-2fd1-4c35-988a-a620dbdb5569,
  abstract     = {In this work we report the coating of a biological template with a polar, but uncharged,luminescent conjugated polymer, soluble in organic solvents but not in water, to produce a nanowire. Amyloid fibrils from bovine insulin were decorated with an alternating polyfluorene derivative. Decorated fibrils were partially aligned on hydrophobic surfaces as separate and<br/><br>
bundled fibrils, by means of molecular combing. The single molecule spectroscopy technique utilizing excitation by rotating linearly polarized light and fluorescence detection through a rotating polarizer showed a high degree of anisotropy of the polymer chains on the individual fibrils. The high degree of polarization indicated highly oriented polymer chains with the preferential orientation of the polymer backbone along the fibrils. The anisotropy ratios are<br/><br>
comparable with those of well-oriented polymer chains in films.},
  author       = {Herland, Anna and Thomsson, Daniel and Mirzov, Oleg and Scheblykin, Ivan and Inganäs, Olle},
  issn         = {1364-5501},
  language     = {eng},
  pages        = {126--132},
  publisher    = {Royal Society of Chemistry},
  series       = {Journal of Materials Chemistry},
  title        = {Decoration of amyloid fibrils with luminescent conjugated polymers},
  url          = {http://dx.doi.org/10.1039/b712829k},
  volume       = {18},
  year         = {2008},
}