The relationship between left ventricular ejection fraction and infarct size assessed by MRI.
(2008) In Scandinavian Cardiovascular Journal 42(2). p.137-145- Abstract
- Objectives. We sought to study the relationship between left ventricular ejection fraction (LVEF) and infarct size in patients with ischemic heart disease (IHD) using magnetic resonance imaging (MRI), and to determine a dysfunction index based on the maximum possible LVEF in relation to infarct size. Design. In 149 patients with chronic IHD, LVEF and infarct size were quantified by MRI. Dysfunction index was defined as the maximum possible LVEF minus measured LVEF. Results. The maximum possible LVEF was found to be LVEF=72.2-[1.18*infarct size]. Dysfunction index for the study population was mean 20 (range -6 to 57), 74% of the study population had a dysfunction index >10 and 44% had a dysfunction index >20. Conclusions. The present... (More)
- Objectives. We sought to study the relationship between left ventricular ejection fraction (LVEF) and infarct size in patients with ischemic heart disease (IHD) using magnetic resonance imaging (MRI), and to determine a dysfunction index based on the maximum possible LVEF in relation to infarct size. Design. In 149 patients with chronic IHD, LVEF and infarct size were quantified by MRI. Dysfunction index was defined as the maximum possible LVEF minus measured LVEF. Results. The maximum possible LVEF was found to be LVEF=72.2-[1.18*infarct size]. Dysfunction index for the study population was mean 20 (range -6 to 57), 74% of the study population had a dysfunction index >10 and 44% had a dysfunction index >20. Conclusions. The present study suggests that infarct size by MRI can be used to estimate a maximum possible LVEF and a dysfunction index. The distribution of dysfunction index in the population suggests a considerable prevalence of dysfunctional but viable myocardium. Future studies are needed to assess if the dysfunction index can be useful to assess the potential for improvement in LVEF following revascularization. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1052165
- author
- Ugander, Martin LU ; Ekmehag, Björn LU and Arheden, Håkan LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Cardiovascular Journal
- volume
- 42
- issue
- 2
- pages
- 137 - 145
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:18365897
- wos:000254350000007
- scopus:41549092337
- pmid:18365897
- ISSN
- 1651-2006
- DOI
- 10.1080/14017430701840317
- language
- English
- LU publication?
- yes
- id
- 883da0ba-d55f-4733-9093-44ba0b3e75af (old id 1052165)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18365897?dopt=Abstract
- date added to LUP
- 2016-04-04 09:14:02
- date last changed
- 2022-03-15 18:20:42
@article{883da0ba-d55f-4733-9093-44ba0b3e75af,
abstract = {{Objectives. We sought to study the relationship between left ventricular ejection fraction (LVEF) and infarct size in patients with ischemic heart disease (IHD) using magnetic resonance imaging (MRI), and to determine a dysfunction index based on the maximum possible LVEF in relation to infarct size. Design. In 149 patients with chronic IHD, LVEF and infarct size were quantified by MRI. Dysfunction index was defined as the maximum possible LVEF minus measured LVEF. Results. The maximum possible LVEF was found to be LVEF=72.2-[1.18*infarct size]. Dysfunction index for the study population was mean 20 (range -6 to 57), 74% of the study population had a dysfunction index >10 and 44% had a dysfunction index >20. Conclusions. The present study suggests that infarct size by MRI can be used to estimate a maximum possible LVEF and a dysfunction index. The distribution of dysfunction index in the population suggests a considerable prevalence of dysfunctional but viable myocardium. Future studies are needed to assess if the dysfunction index can be useful to assess the potential for improvement in LVEF following revascularization.}},
author = {{Ugander, Martin and Ekmehag, Björn and Arheden, Håkan}},
issn = {{1651-2006}},
language = {{eng}},
number = {{2}},
pages = {{137--145}},
publisher = {{Taylor & Francis}},
series = {{Scandinavian Cardiovascular Journal}},
title = {{The relationship between left ventricular ejection fraction and infarct size assessed by MRI.}},
url = {{http://dx.doi.org/10.1080/14017430701840317}},
doi = {{10.1080/14017430701840317}},
volume = {{42}},
year = {{2008}},
}