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Intrauterine growth restriction.

Marsal, Karel LU (2002) In Current Opinion in Obstetrics & Gynecology 14(2). p.127-135
Abstract
Pathophysiological processes underlying intrauterine growth restriction are very complex and poorly understood. Growth restricted fetuses are at risk of hypoxia and, therefore, an early diagnosis of intrauterine growth restriction is important for initiation of fetal surveillance. Application of a three-dimensional ultrasound method for estimation of fetal weight promises better precision. Use of conditional standard deviation scores of fetal biometric variables has been suggested for improved individualized evaluation of intrauterine growth. Application of umbilical artery Doppler velocimetry in the clinical management of growth-restricted fetuses after 32 weeks of gestation leads to decreased perinatal mortality and lower rates of... (More)
Pathophysiological processes underlying intrauterine growth restriction are very complex and poorly understood. Growth restricted fetuses are at risk of hypoxia and, therefore, an early diagnosis of intrauterine growth restriction is important for initiation of fetal surveillance. Application of a three-dimensional ultrasound method for estimation of fetal weight promises better precision. Use of conditional standard deviation scores of fetal biometric variables has been suggested for improved individualized evaluation of intrauterine growth. Application of umbilical artery Doppler velocimetry in the clinical management of growth-restricted fetuses after 32 weeks of gestation leads to decreased perinatal mortality and lower rates of obstetric interventions. Evaluation of fetal state before 32 weeks is difficult and should include Doppler examination of placental circulation and several fetal arterial and venous vessel beds. In addition, recordings of short-term variability of fetal heart rate and biophysical profile have been suggested for fetal surveillance. Important new data on the time sequence of Doppler changes in various vessels of compromised very preterm growth restricted fetuses have been presented, which will enable the establishment of clinical management protocols for evaluation in prospective randomized studies. (Less)
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Contribution to journal
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published
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keywords
Ultrasonography, Doppler, Pregnancy, Placental Circulation : physiology, Inflammation, Human, Homocysteine : physiology, Growth Substances : physiology, Gestational Age, Fetal Weight, Fetal Growth Retardation : etiology, Fetal Growth Retardation : ultrasonography, Prenatal, Umbilical Arteries : ultrasonography, Female, Blood Flow Velocity
in
Current Opinion in Obstetrics & Gynecology
volume
14
issue
2
pages
127 - 135
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000174669500005
ISSN
1473-656X
language
English
LU publication?
yes
id
575083ad-3e0b-477a-b333-ec7d62ff68c2 (old id 107176)
alternative location
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11914689&dopt=Abstract
date added to LUP
2007-07-18 09:48:08
date last changed
2016-04-16 04:47:34
@article{575083ad-3e0b-477a-b333-ec7d62ff68c2,
  abstract     = {Pathophysiological processes underlying intrauterine growth restriction are very complex and poorly understood. Growth restricted fetuses are at risk of hypoxia and, therefore, an early diagnosis of intrauterine growth restriction is important for initiation of fetal surveillance. Application of a three-dimensional ultrasound method for estimation of fetal weight promises better precision. Use of conditional standard deviation scores of fetal biometric variables has been suggested for improved individualized evaluation of intrauterine growth. Application of umbilical artery Doppler velocimetry in the clinical management of growth-restricted fetuses after 32 weeks of gestation leads to decreased perinatal mortality and lower rates of obstetric interventions. Evaluation of fetal state before 32 weeks is difficult and should include Doppler examination of placental circulation and several fetal arterial and venous vessel beds. In addition, recordings of short-term variability of fetal heart rate and biophysical profile have been suggested for fetal surveillance. Important new data on the time sequence of Doppler changes in various vessels of compromised very preterm growth restricted fetuses have been presented, which will enable the establishment of clinical management protocols for evaluation in prospective randomized studies.},
  author       = {Marsal, Karel},
  issn         = {1473-656X},
  keyword      = {Ultrasonography,Doppler,Pregnancy,Placental Circulation : physiology,Inflammation,Human,Homocysteine : physiology,Growth Substances : physiology,Gestational Age,Fetal Weight,Fetal Growth Retardation : etiology,Fetal Growth Retardation : ultrasonography,Prenatal,Umbilical Arteries : ultrasonography,Female,Blood Flow Velocity},
  language     = {eng},
  number       = {2},
  pages        = {127--135},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Current Opinion in Obstetrics & Gynecology},
  title        = {Intrauterine growth restriction.},
  volume       = {14},
  year         = {2002},
}